Review of methods for intraoperative margin detection for breast conserving surgery

BW Maloney, DM McClatchy, BW Pogue… - … of biomedical optics, 2018 - spiedigitallibrary.org
Breast conserving surgery (BCS) is an effective treatment for early-stage cancers as long as
the margins of the resected tissue are free of disease according to consensus guidelines for …

Real-time fluorescence image-guided oncologic surgery

SB Mondal, S Gao, N Zhu, R Liang, V Gruev… - Advances in cancer …, 2014 - Elsevier
Medical imaging plays a critical role in cancer diagnosis and planning. Many of these
patients rely on surgical intervention for curative outcomes. This requires a careful …

Development of a spatially offset Raman spectroscopy probe for breast tumor surgical margin evaluation

MD Keller, E Vargis, N de Matos Granja… - … of biomedical optics, 2011 - spiedigitallibrary.org
The risk of local recurrence for breast cancers is strongly correlated with the presence of a
tumor within 1 to 2 mm of the surgical margin on the excised specimen. Previous …

The status of contemporary image-guided modalities in oncologic surgery

EL Rosenthal, JM Warram, KI Bland, KR Zinn - Annals of surgery, 2015 - journals.lww.com
Objective: To review the current trends in optical imaging to guide oncologic surgery.
Background: Surgical resection remains the cornerstone of therapy for patients with early …

Use of a handheld terahertz pulsed imaging device to differentiate benign and malignant breast tissue

MR Grootendorst, AJ Fitzgerald… - Biomedical Optics …, 2017 - opg.optica.org
Since nearly 20% of breast-conserving surgeries (BCS) require re-operation, there is a clear
need for developing new techniques to more accurately assess tumor resection margins …

Hands-free, wireless goggles for near-infrared fluorescence and real-time image-guided surgery

Y Liu, AQ Bauer, WJ Akers, G Sudlow, K Liang, D Shen… - Surgery, 2011 - Elsevier
Background Current cancer management faces several challenges, including the
occurrence of a residual tumor after resection, the use of radioactive materials or high …

Chromophore based analyses of steady‐state diffuse reflectance spectroscopy: current status and perspectives for clinical adoption

TM Bydlon, R Nachabé, N Ramanujam… - Journal of …, 2015 - Wiley Online Library
Diffuse reflectance spectroscopy is a rapidly growing technology in the biophotonics
community where it has shown promise in its ability to classify different tissues. In the steady …

Evaluating feasibility of an automated 3-dimensional scanner using Raman spectroscopy for intraoperative breast margin assessment

G Thomas, TQ Nguyen, IJ Pence, B Caldwell… - Scientific reports, 2017 - nature.com
Breast conserving surgery is the preferred treatment for women diagnosed with early stage
invasive breast cancer. To ensure successful breast conserving surgeries, efficient tumour …

Polarization-sensitive multimodal imaging for detecting breast cancer

R Patel, A Khan, R Quinlan, AN Yaroslavsky - Cancer research, 2014 - AACR
Intraoperative delineation of breast cancer is a significant problem in surgical oncology. A
reliable method for demarcation of malignant breast tissue during surgery would reduce the …

Optical spectroscopy: current advances and future applications in cancer diagnostics and therapy

DJ Evers, BHW Hendriks, GW Lucassen… - Future …, 2012 - Taylor & Francis
Optical spectroscopy (OS) is a tissue-sensing technique that could enhance cancer
diagnosis and treatment in the near future. With OS, tissue is illuminated with a selected light …