Context Breast cancer is increasing in prevalence in parallel with rising rates of obesity
worldwide. Obesity is recognized as a leading modifiable risk factor for the development of …

Historically, cancer research has focused on identifying mutations or amplification of genes
within the tumor, which informed the development of targeted therapies against affected …

Mediterranean Diet has been recognized as one of the healthiest and sustainable dietary
patterns worldwide, based on the food habits of people living in the Mediterranean region. It …

Obesity, characterized by excess body weight, is now accepted as a hazardous health
condition and an oncogenic factor. In different epidemiological studies obesity has been …

Adiponectin is a cytokine produced predominantly by adipose tissue and correlates with
glucose and lipid homeostasis. However, the effects of adiponectin on endoplasmic …

Highlights•Bone marrow adipose tissue is distinct from white and brown adipose
tissue.•Bone marrow adipose tissue exists in two district populations.•Bone marrow adipose …

Excess body weight and obesity have become significant risk factors for cancer
development. During obesity, adipose tissue alters its biological function, deregulating the …

Obesity is linked to increased cancer risk. Pathological expansion of adipose tissue impacts
adipocyte function and secretion of hormonal factors regulating tissue homeostasis and …

Obesity has a noteworthy role in breast tumor initiation and progression. Among the
mechanisms proposed, the most validated is the development of chronic low-grade …

Background The association between metabolic dysfunction‐associated fatty liver disease
(MAFLD) and hepatocellular carcinoma (HCC) lacks clinical validation in at‐risk …