Connecting the dots in the associations between diet, obesity, cancer, and microRNAs

K Otsuka, H Nishiyama, D Kuriki, N Kawada… - Seminars in cancer …, 2023 - Elsevier
The prevalence of obesity has reached pandemic levels worldwide, leading to a lower
quality of life and higher health costs. Obesity is a major risk factor for noncommunicable …

Adiponectin signaling pathways in liver diseases

T Gamberi, F Magherini, A Modesti, T Fiaschi - Biomedicines, 2018 - mdpi.com
In the liver, adiponectin regulates both glucose and lipid metabolism and exerts an insulin-
sensitizing effect. The binding of adiponectin with its specific receptors induces the activation …

Obesity and multiple myeloma: Emerging mechanisms and perspectives

A Tentolouris, I Ntanasis-Stathopoulos… - Seminars in Cancer …, 2023 - Elsevier
Obesity is a global pandemic that has been associated with the development of breast,
endometrial, large intestine, renal, esophageal, and pancreatic cancer. Obesity is also …

The immune response in adipocytes and their susceptibility to infection: a possible relationship with infectobesity

O López-Ortega, NC Moreno-Corona… - International Journal of …, 2022 - mdpi.com
The current obesity pandemic has been expanding in both developing and developed
countries. This suggests that the factors contributing to this condition need to be …

[HTML][HTML] Cellular mechanisms linking cancers to obesity

XZ Liu, L Pedersen, N Halberg - Cell Stress, 2021 - ncbi.nlm.nih.gov
Obesity is epidemiologically linked to 13 forms of cancer. The local and systemic obese
environment is complex and likely affect tumors through multiple avenues. This includes …

Curcumin and its analogs in non-small cell lung cancer treatment: Challenges and expectations

C Tang, J Liu, C Yang, J Ma, X Chen, D Liu, Y Zhou… - Biomolecules, 2022 - mdpi.com
Researchers have made crucial advances in understanding the pathogenesis and
therapeutics of non-small cell lung cancer (NSCLC), improving our understanding of lung …

Renal cell cancer and obesity

A Gluba-Brzózka, J Rysz, J Ławiński… - International Journal of …, 2022 - mdpi.com
Cancers are a frequent cause of morbidity and mortality. There are many risk factors for
tumours, including advanced age, personal or family history of cancer, some types of viral …

Classic and novel adipocytokines at the intersection of obesity and cancer: diagnostic and therapeutic strategies

N Spyrou, KI Avgerinos, CS Mantzoros… - Current obesity …, 2018 - Springer
Abstract Purpose of Review In this review, we investigate the role of classic and novel
adipocytokines in cancer pathogenesis synopsizing the mechanisms underlying the …

Association of obesity-related metabolic disruptions with cancer risk and outcome

AE Lohmann, PJ Goodwin, RT Chlebowski… - Journal of Clinical …, 2016 - ascopubs.org
Over the past 40 years, the prevalence of obesity has increased epidemically worldwide,
which raises significant concerns regarding public health and the associated economic …

Hepatocellular carcinoma development in diabetic patients: a nationwide survey in Japan

R Tateishi, T Matsumura, T Okanoue, T Shima… - Journal of …, 2021 - Springer
Background Although type 2 diabetes mellitus (T2DM) is a known risk factor for
hepatocellular carcinoma (HCC) development, the annual incidence in diabetes patients is …