Triptolide (TP), a major active and toxic ingredient isolated from the traditional Chinese herb
Tripterygium wilfordii Hook f.(TWHF). A widespread application of TP raises the question on …

Flavones and flavonoids are known to have potent antioxidant activity due to intracellular
free radical scavenging capacities. Flavonoids are found ubiquitously in plants as a member …

Aronia melanocarpa berries (chokeberries) constitute a very rich source of numerous
substances exerting a beneficial impact on health, including mainly polyphenols …

In the last few decades, the scientific community has discovered an immense potential of
natural compounds in the treatment of dreadful diseases such as cancer. Besides the …

The spread of metastatic cancer cell is the main cause of death worldwide. Cellular and
molecular basis of the action of phytochemicals in the modulation of metastatic cancer …

Triptolide (TP), an oxygenated diterpene, has a variety of beneficial pharmacodynamic
activities but its clinical applications are restricted due to severe testicular injury. This study …

Mitochondrial dysfunctions induced by oxidative stress could play a pivotal role in the
development of testicular damage and degeneration, leading to impaired fertility in …

Quercetin is a natural flavonoid widely found in natural fruits and vegetables. Recent studies
have shown that quercetin mediates multiple beneficial effects in a variety of organ damage …

Background Quercetin (QR), is a polyphenolic flavonoid compound which is found in large
amounts in certain foods, and protects against oxidative stress. The current study was …

Triptolide is a predominant active component of Triptergium wilfordii Hook. F, which has
been used for the treatment of cancers and autoimmune diseases such as rheumatoid …