Antibiotic Resistance in Pseudomonas

P Laborda, S Hernando-Amado, JL Martínez… - … and Control Strategies, 2022 - Springer
Pseudomonas is a bacterial genus, with a bona fide environmental habitat that comprises
different species, some of them causing diseases in humans and plants, as well as some …

Genomic Characterization of Carbapenem-Non-susceptible Pseudomonas aeruginosa Clinical Isolates From Saudi Arabia Revealed a Global Dissemination of GES …

M Doumith, S Alhassinah, A Alswaji, M Alzayer… - Frontiers in …, 2022 - frontiersin.org
Carbapenem-resistant P. aeruginosa has become a major clinical problem due to limited
treatment options. However, studies assessing the trends in the molecular epidemiology and …

Overexpression of blaGES-1 due to a strong promoter in the class 1 integron contributes to decreased ceftazidime-avibactam susceptibility in carbapenem-resistant …

X Li, X Zhang, H Cai, Y Zhu, J Ji, T Qu, Y Tu… - Drug Resistance …, 2023 - Elsevier
Abstract Sequence type 235 (ST235) Pseudomonas aeruginosa, harboring so-called
international, high-risk, or widespread clones, is associated with relatively high morbidity …

The intriguing carbapenemases of Pseudomonas aeruginosa: current status, genetic profile, and global epidemiology

DH Halat, CA Moubareck - The Yale Journal of Biology and …, 2022 - search.proquest.com
Worldwide, Pseudomonas aeruginosa remains a leading nosocomial pathogen that is
difficult to treat and constitutes a challenging menace to healthcare systems. P. aeruginosa …

Defeating a superbug: A breakthrough in vaccine design against multidrug-resistant Pseudomonas aeruginosa using reverse vaccinology

S Fereshteh, F Haririzadeh Jouriani… - PLoS …, 2023 - journals.plos.org
Background Multidrug-resistant Pseudomonas aeruginosa has become a major cause of
severe infections. Due to the lack of approved vaccines, this study has presented putative …

Inhibition of multidrug efflux pumps belonging to the major facilitator superfamily in bacterial pathogens

MF Varela, J Stephen, D Bharti, M Lekshmi, S Kumar - Biomedicines, 2023 - mdpi.com
Bacterial pathogens resistant to multiple structurally distinct antimicrobial agents are
causative agents of infectious disease, and they thus constitute a serious concern for public …

Antibiotic concentrations in raw hospital wastewater surpass minimal selective and minimum inhibitory concentrations of resistant Acinetobacter baylyi strains

D Schuster, K Axtmann, N Holstein… - Environmental …, 2022 - Wiley Online Library
Antibiotics are essential for modern medicine, they are employed frequently in hospitals and,
therefore, present in hospital wastewater. Even in concentrations, that are lower than the …

In vitro activity of imipenem/relebactam against Pseudomonas aeruginosa isolates recovered from ICU patients in Spain and Portugal (SUPERIOR and STEP studies …

M Hernández-García, M García-Castillo… - Journal of …, 2022 - academic.oup.com
Objectives To study the in vitro activity of imipenem/relebactam and comparators and the
imipenem/relebactam resistance mechanisms in a Pseudomonas aeruginosa collection …

Spread of GES-5 carbapenemase-producing Pseudomonas aeruginosa clinical isolates in Japan due to clonal expansion of ST235

T Hishinuma, T Tada, K Kuwahara-Arai, N Yamamoto… - PLoS …, 2018 - journals.plos.org
The first outbreak in Japan of GES-5 carbapenemase-producing Pseudomonas aeruginosa
occurred in a long-term care facility in 2014. To assess the spread of GES-5 producing P …

Resistance mechanisms and molecular epidemiology of Pseudomonas aeruginosa strains from patients with bronchiectasis

R Cabrera, L Fernández-Barat… - Journal of …, 2022 - academic.oup.com
Background Non-cystic fibrosis bronchiectasis (BE) is a chronic structural lung condition that
facilitates chronic colonization by different microorganisms and courses with recurrent …