The recent advance of cell-penetrating and tumor-targeting peptides as drug delivery systems based on tumor microenvironment
Q Zhang, N Liu, J Wang, Y Liu, K Wang… - Molecular …, 2023 - ACS Publications
Cancer has become the primary reason for industrial countries death. Although first-line
treatments have achieved remarkable results in inhibiting tumors, they could have serious …
treatments have achieved remarkable results in inhibiting tumors, they could have serious …
Penetrating peptides: Applications in drug delivery
J Xu, F Wang, L Ye, R Wang, L Zhao, X Yang… - Journal of Drug Delivery …, 2023 - Elsevier
Cell-penetrating peptides (CPPs) have gained prominence in intracellular drug delivery due
to their extremely low toxicity and rapid cell internalization property. They present a powerful …
to their extremely low toxicity and rapid cell internalization property. They present a powerful …
Covalent labeling of a chromatin reader domain using proximity-reactive cyclic peptides
Chemical probes for chromatin reader proteins are valuable tools for investigating
epigenetic regulatory mechanisms and evaluating whether the target of interest holds …
epigenetic regulatory mechanisms and evaluating whether the target of interest holds …
Peptide‐Based Nanoarchitectonics for the Treatment of Liver Fibrosis
B Li, Y Huang, Q Zou - ChemBioChem, 2023 - Wiley Online Library
Liver fibrosis is a process of excessive accumulation of extracellular matrix caused by liver
injury. Liver fibrosis can progress to cirrhosis or even liver cancer without proper …
injury. Liver fibrosis can progress to cirrhosis or even liver cancer without proper …
Cell penetrating peptide: A potent delivery system in vaccine development
B Hasannejad-Asl, F Pooresmaeil… - Frontiers in …, 2022 - frontiersin.org
One of the main obstacles to most medication administrations (such as the vaccine
constructs) is the cellular membrane's inadequate permeability, which reduces their …
constructs) is the cellular membrane's inadequate permeability, which reduces their …
[HTML][HTML] Multifunctional building elements for the construction of peptide drug conjugates
L Xu, S Xu, T Xiang, H Liu, L Chen, B Jiang… - Engineered …, 2022 - Elsevier
Engineering of smart building molecules is key basis in designing intelligent drug delivery
systems. As an emerging sophisticated delivery system strategy, the powerful functions of …
systems. As an emerging sophisticated delivery system strategy, the powerful functions of …
[HTML][HTML] Biomaterials-mediated CRISPR/Cas9 delivery: recent challenges and opportunities in gene therapy
AK Dubey, E Mostafavi - Frontiers in Chemistry, 2023 - ncbi.nlm.nih.gov
The use of biomaterials in delivering CRISPR/Cas9 for gene therapy in infectious diseases
holds tremendous potential. This innovative approach combines the advantages of …
holds tremendous potential. This innovative approach combines the advantages of …
Neurog1-derived peptides RMNE1 and DualPep-Shine penetrate the skin and inhibit melanin synthesis by regulating MITF transcription
EC Song, C Park, Y Shin, WK Kim, SB Kim… - International Journal of …, 2023 - mdpi.com
Anti-pigmentation peptides have been developed as alternative skin-lightening agents to
replace conventional chemicals that have adverse effects on the skin. However, the …
replace conventional chemicals that have adverse effects on the skin. However, the …
Uptake pathways of cell-penetrating peptides in the context of drug delivery, gene therapy, and vaccine development
M Dowaidar - Cellular Signalling, 2024 - Elsevier
Cell-penetrating peptides have been extensively utilized for the purpose of facilitating the
intracellular delivery of cargo that is impermeable to the cell membrane. The researchers …
intracellular delivery of cargo that is impermeable to the cell membrane. The researchers …
Magnetic resonance imaging focused on the ferritin heavy chain 1 reporter gene detects neuronal differentiation in stem cells
XY He, YR Zhou, T Mu, YF Liao, L Jiang… - Neural Regeneration …, 2023 - journals.lww.com
The neuronal differentiation of mesenchymal stem cells offers a new strategy for the
treatment of neurological disorders. Thus, there is a need to identify a noninvasive and …
treatment of neurological disorders. Thus, there is a need to identify a noninvasive and …