Compared with traditional drug therapy, nanomedicines exhibit intriguing biological features
to increase therapeutic efficiency, reduce toxicity and achieve targeting delivery. This review …

The relationship between chronic inflammation and neoplastic diseases is not fully
understood. The inflammatory microenvironment of a tumor is an intricate network that …

Systemic and local chronic inflammation might enhance the risk of pancreatic ductal
adenocarcinoma (PDAC), and PDAC-associated inflammatory infiltrate in the tumor …

Acute inflammation is a response to an alteration induced by a pathogen or a physical or
chemical insult, which functions to eliminate the source of the damage and restore …

Increasing evidence demonstrates that radiation acts as an immune stimulus, recruiting
immune mediators that enable anti-tumor responses within and outside the radiation field …

Purpose To provide evidence-based recommendations to oncologists and others for
treatment of patients with locally advanced, unresectable pancreatic cancer. Methods …

BACKGROUND This phase 2 multi‐institutional study was designed to determine whether
gemcitabine (GEM) with fractionated stereotactic body radiotherapy (SBRT) results in …

Objectives: Ablative therapies have been increasingly utilized in the treatment of locally
advanced pancreatic cancer (LAPC). Irreversible electroporation (IRE) is an energy delivery …

Purpose The miniature biodegradable implant siG12D-LODER™ was inserted into a tumor
and released a siRNA drug against KRAS (G12D) along four months. This novel siRNA …

The immune system has the ability to recognize and specifically reject tumors, and tumors
only become clinically apparent once they have evaded immune destruction by creating an …