Contemporary carotid imaging: from degree of stenosis to plaque vulnerability

W Brinjikji, J Huston, AA Rabinstein, GM Kim… - Journal of …, 2016 - thejns.org
Carotid artery stenosis is a well-established risk factor of ischemic stroke, contributing to up
to 10%-20% of strokes or transient ischemic attacks. Many clinical trials over the last 20 …

Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair

W Cai, T Yang, H Liu, L Han, K Zhang, X Hu… - Progress in …, 2018 - Elsevier
Peroxisome proliferator-activated receptor γ (PPARγ) is a widely expressed ligand-
modulated transcription factor that governs the expression of genes involved in …

Oxidative stress and inflammation, key targets of atherosclerotic plaque progression and vulnerability: potential impact of physical activity

P Mury, EN Chirico, M Mura, A Millon, E Canet-Soulas… - Sports Medicine, 2018 - Springer
Atherosclerosis, a complex cardiovascular disease, is a leading cause of mortality and
morbidity worldwide. Oxidative stress and inflammation are both involved in the …

Real-time volumetric assessment of the human carotid artery: handheld multispectral optoacoustic tomography

I Ivankovic, E Merčep, CG Schmedt, XL Deán-Ben… - Radiology, 2019 - pubs.rsna.org
Background Multispectral optical imaging has the capability of resolving hemoglobin, lipid,
and water. Volumetric multispectral optoacoustic tomography (MSOT) is a hybrid imaging …

Ultrasound characteristics of symptomatic carotid plaques: a systematic review and meta-analysis

W Brinjikji, AA Rabinstein, G Lanzino… - Cerebrovascular …, 2015 - karger.com
Background: Ultrasound is the most commonly used imaging modality for assessing carotid
artery stenosis. A number of studies have demonstrated that surface irregularities …

Atherosclerosis Treatment with Stimuli‐Responsive Nanoagents: Recent Advances and Future Perspectives

A Maruf, Y Wang, T Yin, J Huang… - Advanced …, 2019 - Wiley Online Library
Atherosclerosis is the root of approximately one‐third of global mortalities. Nanotechnology
exhibits splendid prospects to combat atherosclerosis at the molecular level by engineering …

[HTML][HTML] Review of imaging biomarkers for the vulnerable carotid plaque

L Saba, N Agarwal, R Cau, C Gerosa, R Sanfilippo… - JVS-Vascular …, 2021 - Elsevier
Identification of carotid artery atherosclerosis is conventionally based on measurements of
luminal stenosis. However, histopathologic studies demonstrate considerable differences …

[HTML][HTML] CT imaging features of carotid artery plaque vulnerability

A Murgia, M Erta, JS Suri, A Gupta… - Annals of …, 2020 - ncbi.nlm.nih.gov
Despite steady advances in medical care, cardiovascular disease remains one of the main
causes of death and long-term morbidity worldwide. Up to 30% of strokes are associated …

Non-invasive in vivo characterization of human carotid plaques with acoustic radiation force impulse ultrasound: comparison with histology after endarterectomy

TJ Czernuszewicz, JW Homeister, MC Caughey… - Ultrasound in medicine …, 2015 - Elsevier
Ischemic stroke from thromboembolic sources is linked to carotid artery atherosclerotic
disease with a trend toward medical management in asymptomatic patients. Extent of …

Cognitive functions in patients after carotid artery revascularization—a narrative review

M Piegza, G Więckiewicz, D Wierzba, J Piegza - Brain Sciences, 2021 - mdpi.com
Carotid revascularization may lead to improved cognitive function beyond stroke prevention.
This article summarizes the conclusions from available studies on the effects of carotid …