Global neurotrauma research challenges and opportunities

AM Rubiano, N Carney, R Chesnut, JC Puyana - Nature, 2015 - nature.com
Traumatic injury to the brain or spinal cord is one of the most serious public health problems
worldwide. The devastating impact of'trauma', a term used to define the global burden of …

From basics to clinical: a comprehensive review on spinal cord injury

NA Silva, N Sousa, RL Reis, AJ Salgado - Progress in neurobiology, 2014 - Elsevier
Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

Systematic rapid" living" review on rehabilitation needs due to COVID-19: update to March 31st, 2020

MG Ceravolo, A De Sire, E Andrenelli… - European journal of …, 2020 - air.unimi.it
INTRODUCTION: The outbreak of COVID-19 epidemics has challenged the provision of
health care worldwide, highlighting the main flaws of some national health systems with …

[HTML][HTML] Antioxidant therapies in traumatic brain and spinal cord injury

M Bains, ED Hall - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2012 - Elsevier
Free radical formation and oxidative damage have been extensively investigated and
validated as important contributors to the pathophysiology of acute central nervous system …

The influence of time from injury to surgery on motor recovery and length of hospital stay in acute traumatic spinal cord injury: an observational Canadian cohort study

MF Dvorak, VK Noonan, N Fallah, CG Fisher… - Journal of …, 2015 - liebertpub.com
To determine the influence of time from injury to surgery on neurological recovery and length
of stay (LOS) in an observational cohort of individuals with traumatic spinal cord injury (tSCI) …

Autologous olfactory ensheathing cell transplantation in human paraplegia: a 3-year clinical trial

A Mackay-Sim, F Feron, J Cochrane… - Brain, 2008 - academic.oup.com
Olfactory ensheathing cells show promise in preclinical animal models as a cell
transplantation therapy for repair of the injured spinal cord. This is a report of a clinical trial of …

Cell therapies for spinal cord injury: a review of the clinical trials and cell-type therapeutic potential

BF Ribeiro, BC da Cruz, BM de Sousa, PD Correia… - Brain, 2023 - academic.oup.com
Spinal cord injury (SCI) is an as yet untreatable neuropathology that causes severe
dysfunction and disability. Cell-based therapies hold neuroregenerative and neuroprotective …

Effect of early vs delayed surgical treatment on motor recovery in incomplete cervical spinal cord injury with preexisting cervical stenosis: a randomized clinical trial

H Chikuda, Y Koyama, Y Matsubayashi… - JAMA network …, 2021 - jamanetwork.com
Importance The optimal management for acute traumatic cervical spinal cord injury (SCI) is
unknown. Objective To determine whether early surgical decompression results in better …

Guidelines for the conduct of clinical trials for spinal cord injury (SCI) as developed by the ICCP panel: clinical trial outcome measures

JD Steeves, D Lammertse, A Curt, JW Fawcett… - Spinal cord, 2007 - nature.com
An international panel reviewed the methodology for clinical trials of spinal cord injury (SCI),
and provided recommendations for the valid conduct of future trials. This is the second of …

Locomotor training for walking after spinal cord injury

J Mehrholz, J Kugler, M Pohl - Cochrane database of …, 2012 - cochranelibrary.com
Background A traumatic spinal cord injury (SCI) is a lesion of neural elements of the spinal
cord that can result in any degree of sensory and motor deficit, autonomic or bowel …