[HTML][HTML] Almost famous: Human adenoviruses (and what they have taught us about cancer)

TM Tessier, MJ Dodge, KM MacNeil, AM Evans… - Tumour Virus …, 2021 - Elsevier
Papillomaviruses, polyomaviruses and adenoviruses are collectively categorized as the
small DNA tumour viruses. Notably, human adenoviruses were the first human viruses …

Cancer‐specific gene therapy

HW Lo, CP Day, MC Hung - Advances in genetics, 2005 - Elsevier
Cancer cells transcriptionally activate many genes that are important for uncontrolled
proliferation and cell death. Deregulated transcriptional machinery in tumor cells usually …

Lycopene supplementation inhibits lung squamous metaplasia and induces apoptosis via up-regulating insulin-like growth factor-binding protein 3 in cigarette smoke …

C Liu, F Lian, DE Smith, RM Russell, XD Wang - Cancer Research, 2003 - AACR
Higher intake of lycopene is related to a lower risk of lung cancer in human studies. Lung
cancer risk is associated with higher plasma levels of insulin-like growth factor I (IGF-I) …

[HTML][HTML] VEGF-specific short hairpin RNA–expressing oncolytic adenovirus elicits potent inhibition of angiogenesis and tumor growth

JY Yoo, JH Kim, YG Kwon, EC Kim, NK Kim, HJ Choi… - Molecular Therapy, 2007 - cell.com
RNA interference is being developed to treat cancer. Although highly target specific, its use
has been limited by its short duration of expression. To overcome this shortcoming, we …

[HTML][HTML] miR-125a regulates angiogenesis of gastric cancer by targeting vascular endothelial growth factor A

J Dai, J Wang, L Yang, Y Xiao… - … journal of oncology, 2015 - spandidos-publications.com
A recent discovery revealed that microRNAs (miRNAs) have an essential effect in the
development and progression of gastric cancer (GC). It has already been shown that miR …

[图书][B] Biomedical physics in radiotherapy for cancer

L Marcu, E Bezak, B Allen - 2012 - books.google.com
The scientific and clinical foundations of Radiation Therapy are cross-disciplinary. This book
endeavours to bring together the physics, the radiobiology, the main clinical aspects as well …

A multicenter Phase I gene therapy clinical trial involving intraperitoneal administration of E1A-lipid complex in patients with recurrent epithelial ovarian cancer …

S Madhusudan, A Tamir, N Bates, E Flanagan… - Clinical cancer …, 2004 - AACR
Abstract Purpose: HER-2/neu oncogene is overexpressed in 10–30% of epithelial ovarian
cancers and is associated with a poor prognosis. The E1A gene product of adenovirus type …

Aging and the programmed death phenomena

VP Skulachev - Model Systems in Aging, 2003 - Springer
Biochemical mechanisms of the programmed death phenomena are considered at levels of
unicellular organisms, mitochondria, cells, groups of cells, and organs. Some examples of …

[HTML][HTML] Oncolytic effects of adenovirus mutant capable of replicating in hypoxic and normoxic regions of solid tumor

WK Cho, YR Seong, YH Lee, MJ Kim, KS Hwang… - Molecular Therapy, 2004 - cell.com
Solid tumors contain normoxic and hypoxic regions depending on the distance from the
capillary. Normal cells may also be exposed to hypoxia under certain physiological …

Systemic Gene Therapy in Human Xenograft Tumor Models by Liposomal Delivery of the E1A Gene

NT Ueno, C Bartholomeusz, W Xia, P Anklesaria… - Cancer research, 2002 - AACR
The adenovirus type 5 E1A protein has been demonstrated to elicit antitumor effects through
the induction of apoptosis, inhibition of cell cycle progression, induction of differentiated …