Post‐transcriptional gene silencing targets and degrades mRNA transcripts, silencing the
expression of specific genes. RNA interference technology, using synthetic structurally well …

A large body of evidence implicates the renin–angiotensin system in the pathogenesis of
cardiovascular disease. However, not everyone understands that the magnitude of the risk …

Hypertension is an extremely common noncom-municable condition affecting an estimated
1.3 billion adults (aged 30–79 years) worldwide and with a prevalence that has doubled …

Hypertension is a significant and increasing global health issue. It is a leading cause of
cardiovascular disease and premature death worldwide due to its effects on end organs …

The renin-angiotensin-aldosterone system (RAAS) is a well-defined pathway playing a key
role in maintaining circulatory homeostasis. Abnormal activation of RAAS contributes to …

The identification of an alternate extended form of angiotensin I composed of the first twelve
amino acids at the N-terminal of angiotensinogen has generated new knowledge of the …

The COVID-19 pandemic has led to a renewed recognition of the importance of disease
prevention and public health globally. The progress in COVID-19 vaccine technology is a …

The prevalence of arterial hypertension is approximately 47% in the United States and 55%
in Europe. Multiple different medical therapies are used to treat hypertension including …

Hypertension is a common noncommunicable condition estimated to affect over one billion
adults worldwide, with a prevalence that has doubled over the past 20 years [1]. From 2012 …

We engineered a monoclonal antibody (mAb) against the human C-terminus of angiotensin-
(1–12)[h-Ang-(1–12)] and performed a biochemical characterization in concert with direct in …