As influenza-A viruses (IAV) replicate in the host cell nucleus, intranuclear pathways are
usurped for viral gene expression. The eight genomic viral ribonucleoproteins (vRNPs) …

RNA-binding proteins (RBPs) have emerged as important players in multiple biological
processes including transcription regulation, splicing, R-loop homeostasis, DNA …

In addition to antioxidative and anti-inflammatory properties, activators of the cytoprotective
nuclear factor erythroid-2-like-2 (NRF2) signaling pathway have antiviral effects, but the …

Tripartite motif-containing protein 21 (TRIM21), an E3 ubiquitin ligase, plays a critical role in
the host antiviral response. However, the mechanism and antiviral spectrum of TRIM21 in …

Protein modifications dynamically occur and regulate biological processes in all organisms.
Towards understanding the significance of protein modifications in influenza virus infection …

RIG-I-like receptors (RLRs), retinoic acid inducible gene I (RIG-I) and melanoma
differentiation-associated protein 5 (MDA5), are pattern recognition receptors through which …

Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) plays an important role in
regulating the replication of many viruses. However, it remains elusive whether and how …

The first line of defense against viral infection of the host cell is the cellular lipid membrane,
which is also a crucial first site of contact for viruses. Lipids may sometimes be used as viral …

The host interactome of influenza viral proteins is ever-expanding. In this work, we report the
identification of host heterogeneous nuclear ribonucleoprotein C (hnRNP-C) as an …

Alternative RNA splicing is a co-transcriptional process that richly increases proteome
diversity, and is dynamically regulated based on cell species, lineage, and activation state …