Unraveling the serotonin saga: from discovery to weight regulation and beyond-a comprehensive scientific review

K Conde, S Fang, Y Xu - Cell & Bioscience, 2023 - Springer
The prevalence of obesity is rapidly increasing worldwide, while the development of
effective obesity therapies lags behind. Although new therapeutic targets to alleviate obesity …

Advanced neurobiological tools to interrogate metabolism

PN Mirabella, H Fenselau - Nature Reviews Endocrinology, 2023 - nature.com
Engineered neurobiological tools for the manipulation of cellular activity, such as
chemogenetics and optogenetics, have become a cornerstone of modern neuroscience …

[HTML][HTML] Dorsal raphe serotonergic neurons suppress feeding through redundant forebrain circuits

I Aklan, N Sayar-Atasoy, F Deng, H Kim, Y Yavuz… - Molecular …, 2023 - Elsevier
Objective Serotonin (5HT) is a well-known anorexigenic molecule, and 5HT neurons of
dorsal raphe nucleus (DRN) have been implicated in suppression of feeding; however, the …

Serotonergic regulation of appetite and sodium appetite

Y Shin, S Kim, JW Sohn - Journal of Neuroendocrinology, 2023 - Wiley Online Library
Serotonin is a neurotransmitter that is synthesized and released from the brainstem raphe
nuclei to affect many brain functions. It is well known that the activity of raphe serotonergic …

[HTML][HTML] Modulation of GABA release by 5-HT1B receptors: An interplay with AMPA-receptors and voltage-gated Ca2+ channels

DAN Al-Halboosi, O Savchenko, LK Heisler… - …, 2023 - Elsevier
Obesity has become a worldwide health challenge and commonly results from the intake of
more calories than the body requires. The brain represents the master controller of food …