Unraveling the serotonin saga: from discovery to weight regulation and beyond-a comprehensive scientific review
The prevalence of obesity is rapidly increasing worldwide, while the development of
effective obesity therapies lags behind. Although new therapeutic targets to alleviate obesity …
effective obesity therapies lags behind. Although new therapeutic targets to alleviate obesity …
Advanced neurobiological tools to interrogate metabolism
PN Mirabella, H Fenselau - Nature Reviews Endocrinology, 2023 - nature.com
Engineered neurobiological tools for the manipulation of cellular activity, such as
chemogenetics and optogenetics, have become a cornerstone of modern neuroscience …
chemogenetics and optogenetics, have become a cornerstone of modern neuroscience …
[HTML][HTML] Dorsal raphe serotonergic neurons suppress feeding through redundant forebrain circuits
Objective Serotonin (5HT) is a well-known anorexigenic molecule, and 5HT neurons of
dorsal raphe nucleus (DRN) have been implicated in suppression of feeding; however, the …
dorsal raphe nucleus (DRN) have been implicated in suppression of feeding; however, the …
Serotonergic regulation of appetite and sodium appetite
Y Shin, S Kim, JW Sohn - Journal of Neuroendocrinology, 2023 - Wiley Online Library
Serotonin is a neurotransmitter that is synthesized and released from the brainstem raphe
nuclei to affect many brain functions. It is well known that the activity of raphe serotonergic …
nuclei to affect many brain functions. It is well known that the activity of raphe serotonergic …
[HTML][HTML] Modulation of GABA release by 5-HT1B receptors: An interplay with AMPA-receptors and voltage-gated Ca2+ channels
DAN Al-Halboosi, O Savchenko, LK Heisler… - …, 2023 - Elsevier
Obesity has become a worldwide health challenge and commonly results from the intake of
more calories than the body requires. The brain represents the master controller of food …
more calories than the body requires. The brain represents the master controller of food …