[HTML][HTML] RNA combined with nanoformulation to advance therapeutic technologies

ES Lima, D Dos Santos, AL Souza, ME Macedo… - Pharmaceuticals, 2023 - mdpi.com
Nucleic acid-based therapies have the potential to address numerous diseases that pose
significant challenges to more traditional methods. RNA-based therapies have emerged as …

[HTML][HTML] The nexus of inflammation-induced epithelial-mesenchymal transition and lung cancer progression: a roadmap to pentacyclic triterpenoid-based therapies

KV Odarenko, MA Zenkova, AV Markov - International Journal of …, 2023 - mdpi.com
Lung cancer is the leading cause of cancer-related death worldwide. Its high mortality is
partly due to chronic inflammation that accompanies the disease and stimulates cancer …

A potential cure for tumor‐associated immunosuppression by Toxoplasma gondii

N Lotfalizadeh, S Sadr, S Morovati… - Cancer …, 2024 - Wiley Online Library
Background Recently, immunotherapy has become very hopeful for cancer therapy. Cancer
treatment through immunotherapy has excellent specificity and less toxicity than …

E3 ubiquitin ligases in lung cancer: Emerging insights and therapeutic opportunities

B Basu, S Kal, S Karmakar, M Basu, MK Ghosh - Life Sciences, 2023 - Elsevier
Aim In this review, we have attempted to provide the readers with an updated account of the
role of a family of proteins known as E3 ligases in different aspects of lung cancer …

Therapeutic Targeting of Lung Adenocarcinoma with Mannose-Coated Chitosan/Copper Nanocluster–Levocetirizine Nanocomposite

K Choudhury, A Chattopadhyay… - ACS Applied Nano …, 2023 - ACS Publications
Lung adenocarcinoma is regarded as the most common form of lung cancer, per the latest
epidemiological data. The combined efforts from chemotherapy and radiotherapy have done …

[HTML][HTML] Lung inflammation perturbation by engineered nanoparticles

X Zhou, W Jin, J Ma - Frontiers in Bioengineering and Biotechnology, 2023 - frontiersin.org
In recent years, the unique and diverse physicochemical properties of nanoparticles have
brought about their wide use in many fields; however, it is necessary to better understand …

Targeting PARP14 with lomitapide suppresses drug resistance through the activation of DRP1-induced mitophagy in multiple myeloma

H Zhang, H Wang, Y Hu, Y Gao, J Chen, Y Meng, Y Qiu… - Cancer Letters, 2024 - Elsevier
Multiple myeloma (MM) is a hematological malignancy that remains incurable, primarily due
to the high likelihood of relapse or development of resistance to current treatments. To …

[HTML][HTML] Advances in Non-Small Cell Lung Cancer (NSCLC) Treatment—A Paradigm Shift in Oncology

A Ali - Pharmaceuticals, 2024 - mdpi.com
Non-Small Cell Lung Cancer (NSCLC) management remains a formidable challenge in the
field of oncology, representing a significant global health burden. However, recent years …

[HTML][HTML] In silico evaluation of binding interaction and ADME study of new 1, 3-diazetidin-2-one derivatives with high antiproliferative activity

FH Abdulredha, MF Mahdi, AK Khan - Journal of Advanced …, 2023 - journals.lww.com
A series of eight novels'1, 3-diazetidin-2-ones have been proposed to assess their potential
activities. They are intended to examine antiproliferative effects through inhibition of …

Network‐based identification of key proteins and repositioning of drugs for non‐small cell lung cancer

OM Adeyemo, Z Ashimiyu‐Abdusalam… - Cancer …, 2024 - Wiley Online Library
Background NSCLC is a lethal cancer that is highly prevalent and accounts for 85% of cases
of lung cancer. Conventional cancer treatments, such as chemotherapy and radiation …