The immune microenvironment in gastric adenocarcinoma

Y Zavros, JL Merchant - Nature Reviews Gastroenterology & …, 2022 - nature.com
Like most solid tumours, the microenvironment of epithelial-derived gastric adenocarcinoma
(GAC) consists of a variety of stromal cell types, including fibroblasts, and neuronal …

[HTML][HTML] Digesting the role of JAK-STAT and cytokine signaling in oral and gastric cancers

Y Ni, JT Low, J Silke, LA O'Reilly - Frontiers in Immunology, 2022 - frontiersin.org
When small proteins such as cytokines bind to their associated receptors on the plasma
membrane, they can activate multiple internal signaling cascades allowing information from …

Association of Helicobacter pylori Infection and Host Cytokine Gene Polymorphism with Gastric Cancer

M Zeyaullah, AM AlShahrani… - Canadian Journal of …, 2021 - Wiley Online Library
The global cancer burden of new cases of various types rose with millions of death in 2018.
Based on the data extracted by GLOBOCAN 2018, gastric cancer (GC) is the third leading …

The clinicopathological characteristics of gastric cancer and precancerous conditions in gastric DLBCL and MALT lymphoma patients: a multi-center retrospective …

Y Feng, TJ Duan, Q Huang, ZY Li, YP Liu… - Annals of …, 2023 - Taylor & Francis
Objective The objective of this study is to explore the clinicopathological characteristics of
gastric cancer and precancerous conditions in patients with primary gastric lymphoma …

[HTML][HTML] Molecular alterations in gastric intestinal metaplasia

P Jonaitis, L Kupcinskas, J Kupcinskas - International journal of molecular …, 2021 - mdpi.com
Gastric cancer (GC) remains one of the most common causes of mortality worldwide.
Intestinal metaplasia (IM) is one of the preneoplastic gastric lesions and is considered an …

Potential Non-invasive Biomarkers of Helicobacter pylori-Associated Gastric Cancer

F Boubrik, A Belmouden, N El Kadmiri - Journal of Gastrointestinal Cancer, 2022 - Springer
Background Gastric cancer (GC) remains the fifth most common incident cancer with the
highest incidence in East Asian countries and the third leading cause of cancer death …

[HTML][HTML] IL-17 receptor signaling through IL-17A or IL-17F is sufficient to maintain innate response and control of Helicobacter pylori immunopathogenesis

BREA Dixon, TJ Lee, DC Contreras Healey, J Li… - …, 2022 - journals.aai.org
IL-17R signaling is required for control of extracellular pathogens and is also implicated in
development of chronic inflammatory processes. The response to the human pathogen …

[HTML][HTML] Helicobacter pylori infection over bile reflux: No influence on the severity of endoscopic or premalignant gastric lesion development

A Szőke, S Mocan, A Negovan - Experimental and …, 2021 - spandidos-publications.com
Helicobacter (H.) pylori infection and duodenogastric reflux (DGR) are both linked to
endoscopic and premalignant gastric lesion development, but it is still unclear whether they …

Prevalence of gastric preneoplastic lesions in first-degree relatives of patients with gastric cancer: a cross-sectional study

S Sotelo, C Manterola, T Otzen, E Morales… - Journal of …, 2023 - Springer
Purpose Worldwide, gastric cancer (GC) is the 5th cancer with the highest incidence and the
4th in mortality. To reduce it, one strategy is to diagnose preneoplastic lesions (PNL) …

The role of Serum Interleukin-4 and Interleukin-6 in Helicobacter pylori-infected patients

KH Rasool, AEM Alubadi, IFI Al-Bayati - Microbial Pathogenesis, 2022 - Elsevier
Background Helicobacter pylori (H. pylori) is a Gram-negative bacteria that colonizes the
gastrointestinal mucosa and causes chronic inflammation. Aims There are several studies …