Cocaine addiction disorder is notably aggravated by concomitant cognitive and emotional
pathology that impedes recovery. We studied whether a persistent cognitive/emotional …

How neurons in the medial prefrontal cortex broadcast stress-relevant information to
subcortical brain sites to regulate cocaine relapse remains unclear. The lateral habenula …

Anxiety is one of the most common comorbid conditions reported in people with opioid
dependence. The basolateral amygdala (BLA) and ventral hippocampus (vHip) are critical …

Erasing memories of cocaine–stimuli associations might have important clinical implications
for addiction therapy. Stimulating hippocampal plasticity by enhancing adult hippocampal …

Studies of personality have suggested that dissimilarities in ability to cope with stressful
situations results in differing tendency to develop addictive behaviors. The present study …

Cocaine induces neuroinflammatory response and interleukin-1 beta (IL1β) is suggested a
final effector for many cocaine-induced inflammatory signals. Recently, the chemokine …

Prenatal stress (PS) induces long-lasting molecular alterations in brain circuits of the
offspring and increases the propensity to develop neuropsychiatric diseases during …

Background: One challenge in the treatment of substance use disorders is to re-engage the
interest toward non-drug-related activities. Among these activities, social interaction has had …

Cocaine is the most prevalent illegal stimulant drug in Europe among the adult population.
Its abuse is characterized by a faster substance abuse disorder (SUD) development than …

Recent research suggests that exercise may help facilitate abstinence from cocaine
addiction, though the mechanisms are not well understood. In mice, wheel running …