[HTML][HTML] Frequency-domain techniques for cerebral and functional near-infrared spectroscopy
S Fantini, A Sassaroli - Frontiers in neuroscience, 2020 - frontiersin.org
This article reviews the basic principles of frequency-domain near-infrared spectroscopy (FD-
NIRS), which relies on intensity-modulated light sources and phase-sensitive optical …
NIRS), which relies on intensity-modulated light sources and phase-sensitive optical …
Advances in fluorescence microscopy techniques to study kidney function
Fluorescence microscopy, in particular immunofluorescence microscopy, has been used
extensively for the assessment of kidney function and pathology for both research and …
extensively for the assessment of kidney function and pathology for both research and …
Fit-free analysis of fluorescence lifetime imaging data using the phasor approach
Fluorescence lifetime imaging microscopy (FLIM) is used in diverse disciplines, including
biology, chemistry and biophysics, but its use has been limited by the complexity of the data …
biology, chemistry and biophysics, but its use has been limited by the complexity of the data …
[HTML][HTML] An autism spectrum disorder-related de novo mutation hotspot discovered in the GEF1 domain of Trio
The Rho guanine nucleotide exchange factor (RhoGEF) Trio promotes actin polymerization
by directly activating the small GTPase Rac1. Recent studies suggest that autism spectrum …
by directly activating the small GTPase Rac1. Recent studies suggest that autism spectrum …
[HTML][HTML] Structural and functional characterization of human stem-cell-derived retinal organoids by live imaging
AW Browne, C Arnesano… - … & visual science, 2017 - iovs.arvojournals.org
Purpose: Human pluripotent stem cell (hPSC)-derived retinal organoids are a platform for
investigating retinal development, pathophysiology, and cellular therapies. In contrast to …
investigating retinal development, pathophysiology, and cellular therapies. In contrast to …
[HTML][HTML] Imaging fibrosis and separating collagens using second harmonic generation and phasor approach to fluorescence lifetime imaging
In this paper we have used second harmonic generation (SHG) and phasor approach to
auto fluorescence lifetime imaging (FLIM) to obtain fingerprints of different collagens and …
auto fluorescence lifetime imaging (FLIM) to obtain fingerprints of different collagens and …
[HTML][HTML] Recent advances in high speed diffuse optical imaging in biomedicine
Diffuse optical imaging (DOI) is a label-free, safe, inexpensive, and quantitative imaging
modality that provides metabolic and molecular contrast in tissue using visible or near …
modality that provides metabolic and molecular contrast in tissue using visible or near …
[HTML][HTML] Label-free fluorescence lifetime and second harmonic generation imaging microscopy improves quantification of experimental renal fibrosis
S Ranjit, E Dobrinskikh, J Montford, A Dvornikov… - Kidney international, 2016 - Elsevier
All forms of progressive renal diseases develop a final pathway of tubulointerstitial fibrosis
and glomerulosclerosis. Renal fibrosis is usually quantified using histological staining, a …
and glomerulosclerosis. Renal fibrosis is usually quantified using histological staining, a …
Multicomponent analysis of phasor plot in a single pixel to calculate changes of metabolic trajectory in biological systems
Phasor FLIM in cells undergoing oxidative stress and in mice liver sections have shown the
presence of a third autofluorescent component indicative of lipid droplets along with free and …
presence of a third autofluorescent component indicative of lipid droplets along with free and …
Measuring the effect of a Western diet on liver tissue architecture by FLIM autofluorescence and harmonic generation microscopy
S Ranjit, A Dvornikov, E Dobrinskikh… - Biomedical optics …, 2017 - opg.optica.org
The phasor approach to auto-fluorescence lifetime imaging was used to identify and
characterize a long lifetime species (LLS)(~ 7.8 ns) in livers of mice fed with a Western diet …
characterize a long lifetime species (LLS)(~ 7.8 ns) in livers of mice fed with a Western diet …