Brain tumors are a heterogeneous group of neoplasms ranging from almost benign to highly
aggressive phenotypes. The malignancy of these tumors mostly relies on gene expression …

Medulloblastoma (MB), grouped as either WNT‑activated, Sonic hedgehog (SHH)‑activated,
or non-WNT/non-SHH group 3, accounts for almost 20% of all childhood brain cancers. In …

Background MYC amplification or overexpression is common in Group 3 medulloblastoma
and is associated with the worst prognosis. Recently, protein arginine methyl transferase …

Background Endocrine deficiencies are common following Craniospinal irradiation (CSI) in
children with brain tumors, but empirical data comparing outcomes following proton (PRT) …

Medulloblastoma, the most common primary pediatric malignant brain tumor is a molecularly
heterogeneous disease with different developmental origins, distinct phenotypes, diverse …

Medulloblastoma is the most common embryonal tumor in children. The current standard of
care comprises surgical resection, radiation and chemotherapy. Patients are stratified into …

Methods: The Indian Society of Neuro-Oncology (ISNO) constituted an expert multi-
disciplinary panel with adequate representation from all stakeholders to prepare national …

Medulloblastoma is the most common malignant brain tumor of childhood and remains a
major cause of cancer related mortality in children. Significant scientific advancements have …

Background Medulloblastoma (MB) is the most common malignant brain tumor during
childhood. Circular RNA (circSKA3) was identified to function as an oncogene in MB …

Medulloblastoma (MB) is the most common malignant brain tumor in children. Current
treatment for MB includes surgical resection, radiotherapy and chemotherapy. Despite …