Adenosine A2A receptors and their role in drug addiction
The specific events between initial presumably manageable drug intake and the
development of a drug‐addicted state are not yet known. Drugs of abuse have varying …
development of a drug‐addicted state are not yet known. Drugs of abuse have varying …
A1-adenosine receptor gene expression in fetal rat brain
DR Weaver - Developmental brain research, 1996 - Elsevier
Adenosine influences neurotransmitter release, neuronal excitability, and firing rate, through
A1-adenosine receptors (A1-R). Caffeine and related methylxanthines are adenosine …
A1-adenosine receptors (A1-R). Caffeine and related methylxanthines are adenosine …
[HTML][HTML] The fat mass and obesity-associated protein (FTO) regulates locomotor responses to novelty via D2R medium spiny neurons
J Ruud, J Alber, A Tokarska, LE Ruud, H Nolte… - Cell Reports, 2019 - cell.com
Variations in the human FTO gene have been linked to obesity and altered connectivity of
the dopaminergic neurocircuitry. Here, we report that fat mass and obesity-associated …
the dopaminergic neurocircuitry. Here, we report that fat mass and obesity-associated …
Adenosine A2A receptor interactions with receptors for other neurotransmitters and neuromodulators
JA Ribeiro - European journal of pharmacology, 1999 - Elsevier
Adenosine, by activating adenosine A2A receptors, seems to have a crucial function in
regulating the activation of multiple receptors that affect neurotransmitter release and/or …
regulating the activation of multiple receptors that affect neurotransmitter release and/or …
Adenosine A2A receptor antagonists and Parkinson's disease: state of the art and future directions
N Simola, M Morelli, A Pinna - Current pharmaceutical design, 2008 - ingentaconnect.com
Adenosine A2A receptors present in the central nervous system have been implicated in the
modulation of motor functions. Accordingly, adenosine A2A receptor antagonists currently …
modulation of motor functions. Accordingly, adenosine A2A receptor antagonists currently …
[HTML][HTML] DARPP-32: from neurotransmission to cancer
A Belkhiri, S Zhu, W El-Rifai - Oncotarget, 2016 - ncbi.nlm.nih.gov
Dopamine and cAMP-regulated phosphoprotein Mr 32,000 (DARPP-32), also known as
phosphoprotein phosphatase-1 regulatory subunit 1B (PPP1R1B), was initially discovered …
phosphoprotein phosphatase-1 regulatory subunit 1B (PPP1R1B), was initially discovered …
FACS array profiling identifies Ecto-5′ nucleotidase as a striatopallidal neuron-specific gene involved in striatal-dependent learning
SL Ena, JF De Backer, SN Schiffmann… - Journal of …, 2013 - Soc Neuroscience
The striatopallidal (STP) and striatonigral (STN) neurons constitute the main neuronal
populations of the striatum. Despite the increasing knowledge concerning their involvement …
populations of the striatum. Despite the increasing knowledge concerning their involvement …
Functional Uncoupling of Adenosine A2A Receptors and Reduced Response to Caffeine in Mice Lacking Dopamine D2Receptors
NR Zahniser, JK Simosky, RD Mayfield… - Journal of …, 2000 - Soc Neuroscience
Dopamine D2 receptors (Rs) and adenosine A2ARs are coexpressed on striatopallidal
neurons, where they mediate opposing actions. In agreement with the idea that D2Rs …
neurons, where they mediate opposing actions. In agreement with the idea that D2Rs …
Genetic and pharmacological inactivation of the adenosine A2A receptor attenuates 3‐nitropropionic acid‐induced striatal damage
Abstract Adenosine A2A receptor (A2AR) antagonism attenuates 1‐methyl‐4‐phenyl‐1, 2, 3,
6‐tetrahydropyridine‐induced dopaminergic neurodegeneration and quinolinic acid …
6‐tetrahydropyridine‐induced dopaminergic neurodegeneration and quinolinic acid …
Activation of dopamine D2 receptors decreases DARPP-32 phosphorylation in striatonigral and striatopallidal projection neurons via different mechanisms
M Lindskog, P Svenningsson, BB Fredholm… - Neuroscience, 1999 - Elsevier
The vast majority of striatal neurons are GABAergic medium-sized spiny neurons. These
cells receive glutamatergic input from the cortex, thalamus and limbic areas and …
cells receive glutamatergic input from the cortex, thalamus and limbic areas and …