Background & Aims The management of inflammatory bowel disease (IBD) poses a
particular challenge during pregnancy because the health of both the mother and the fetus …

Trying to conceive and being pregnant is an emotional period for those involved. In the
majority of patients suffering from inflammatory bowel disease, maintenance therapy is …

Background Women with chronic inflammatory diseases face uncertainty regarding the
safety of biologics during breast feeding. CRADLE was the first industry-sponsored study to …

1.0 Background Psoriasis is a common, chronic inflammatory skin disease which typically
follows a relapsing and remitting course, and is associated with joint disease in …

Background & Aims Exposure to biologic and immunosuppressant agents during
breastfeeding is controversial, and there are limited data on safety. We investigated whether …

There are profound differences in maternofetal transfer of immunoglobulins between
species with extensive gestational transfer of maternal immunoglobulins in primates …

Inflammatory bowel diseases (IBD) typically affect patients in their reproductive years. It has
been shown that reproductive issues are of key concern to IBD patients, 1 especially …

Background Tumor necrosis factor (TNF)-α inhibitors are increasingly being used in
inflammatory bowel disease (IBD). Because this chronic intestinal disorder often affects …

OBJECTIVES: Anti-tumor necrosis factor (TNF) drugs are an effective therapeutic option in
patients with inflammatory bowel disease (IBD). However, data regarding their safety during …

Biologic therapies have revolutionized treatment outcomes for patients with inflammatory
arthritis. However, there remains a concern regarding their safety during conception …