Inactivation of ERK1/2 signaling in dopaminergic neurons by map kinase phosphatase MKP3 regulates dopamine signaling and motivation for cocaine
DL Bernstein, SI Lewandowski, C Besada… - Journal of …, 2024 - Soc Neuroscience
The mesolimbic dopamine system is a crucial component of reward and reinforcement
processing, including the psychotropic effects of drugs of abuse such as cocaine. Drugs of …
processing, including the psychotropic effects of drugs of abuse such as cocaine. Drugs of …
[HTML][HTML] Hypocretin/orexin receptor 1 knockdown in GABA or dopamine neurons in the ventral tegmental area differentially impact mesolimbic dopamine and …
The hypocretins/orexins (HCRT) have been demonstrated to influence motivation for
cocaine through actions on dopamine (DA) transmission. Pharmacological or genetic …
cocaine through actions on dopamine (DA) transmission. Pharmacological or genetic …
[HTML][HTML] Opposing Spatially Segregated Function of Endogenous GDNF-RET Signaling in Cocaine Addiction
DR Garton, G Turconi, V Iivanainen, JO Andressoo - Biomolecules, 2023 - mdpi.com
Cocaine addiction is a serious condition with potentially lethal complications and no current
pharmacological approaches towards treatment. Perturbations of the mesolimbic dopamine …
pharmacological approaches towards treatment. Perturbations of the mesolimbic dopamine …
Fast Scan Cyclic Voltammetry to Assess Dopamine Function: From Circuits to Behavior
Electrochemical techniques have allowed investigators to measure analytes of interest for
decades. Of these techniques, fast scan cyclic voltammetry (FSCV) offers advantages that …
decades. Of these techniques, fast scan cyclic voltammetry (FSCV) offers advantages that …
[PDF][PDF] Opposing Spatially Segregated Function of Endogenous GDNF-RET Signaling in Cocaine Addiction. Biomolecules 2023, 13, 761
DR Garton, G Turconi, V Iivanainen, JO Andressoo - 2023 - helda.helsinki.fi
Cocaine addiction is a serious condition with potentially lethal complications and no current
pharmacological approaches towards treatment. Perturbations of the mesolimbic dopamine …
pharmacological approaches towards treatment. Perturbations of the mesolimbic dopamine …
Targeting Hypocretin Receptor 1 to Normalize Nucleus Accumbens Dopamine Transmission and Block Incubation of Cocaine Seeking
PJ Clark - 2022 - search.proquest.com
Cocaine use disorder is a devastating condition for which there are no approved
pharmacotherapies. A robust body of work indicates that Nucleus Accumbens (NAc) …
pharmacotherapies. A robust body of work indicates that Nucleus Accumbens (NAc) …