Venous thromboembolism (VTE) refers to deep vein thrombosis (DVT), whose consequence
may be a pulmonary embolism (PE). Thrombosis is associated with significant morbidity and …

Platelets have a crucial role in haemostasis and atherothrombosis. Pharmacological control
of platelet hyper-reactivity has become a cornerstone in the prevention of thrombo …

Cardiovascular disease remains one of the world's leading causes of death. Myocardial
infarction (heart attack) is triggered by occlusion of coronary arteries by platelet-rich thrombi …

Distinct platelet activation patterns are elicited by the tyrosine kinase-linked collagen
receptor glycoprotein VI (GPVI) and the G-protein coupled protease-activated receptors …

Platelets are important cellular targets in cardiovascular disease. Based on insights from
basic science, translational approaches and clinical studies, a distinguished anti-platelet …

Leaf extracts from Chilean bean landraces were assessed for antiplatelet activity using
different assays in vitro. Lyophilized MeOH: H 2 O 7: 3 (v/v) and EtOH: H 2 O 7: 3 (v/v) leaf …

Implantable Cardiovascular Therapeutic Devices (CTD), while lifesaving, impart
supraphysiologic shear stress to platelets, resulting in thrombotic and bleeding …

P2Y 12 is a platelet surface protein which is responsible for the amplification of P2Y 1
response. It plays a crucial role in platelet aggregation and thrombus formation through an …

Background Despite a reduction in the rate of thrombotic events, ischemic heart disease
(IHD) remains a key medical problem associated with high major bleeding and mortality in …

Cardiovascular diseases (CVDs) account for over 17 million death globally each year,
including arterial thrombosis. Platelets are key components in the pathogenesis of this …