[HTML][HTML] The role of Exosomal miRNAs in cancer

C Li, T Zhou, J Chen, R Li, H Chen, S Luo… - Journal of translational …, 2022 - Springer
Exosomal miRNAs have attracted much attention due to their critical role in regulating genes
and the altered expression of miRNAs in virtually all cancers affecting humans (Sun et al. in …

Exosomes: Isolation, characterization, and biomedical applications

GN Alzhrani, ST Alanazi, SY Alsharif… - Cell Biology …, 2021 - Wiley Online Library
Exosomes are nano‐sized bioactive vesicles of 30–150 nm in diameter. They are secreted
by exocytosis of nearly all type of cells in to the extracellular fluid. Thereby, they can be …

Simultaneous detection of tumor derived exosomal protein–microRNA pairs with an Exo-PROS biosensor for cancer diagnosis

CC Hsu, Y Yang, E Kannisto, X Zeng, G Yu… - ACS …, 2023 - ACS Publications
Tumor derived exosomes (TEXs) have emerged as promising biomarkers for cancer liquid
biopsy. Conventional methods (such as ELISA and qRT-PCR) and emerging biosensing …

[HTML][HTML] Comparison of serum and plasma as a source of blood extracellular vesicles: Increased levels of platelet-derived particles in serum extracellular vesicle …

X Zhang, T Takeuchi, A Takeda, H Mochizuki… - PLoS One, 2022 - journals.plos.org
Extracellular vesicles (EVs) have attracted much attention as potential diagnostic biomarkers
for human diseases. Although both plasma and serum are utilized as a source of blood EVs …

Electrochemical biosensors in exosome analysis; a short journey to the present and future trends in early-stage evaluation of cancers

E Dezhakam, B Khalilzadeh, M Mahdipour… - Biosensors and …, 2023 - Elsevier
The tumor microenvironment consists of a multiplicity of cells such as cancer cells,
fibroblasts, endothelial cells, and immune cells within the specific parenchyma. It has been …

[HTML][HTML] MicroRNAs in extracellular vesicles: sorting mechanisms, diagnostic value, isolation, and detection technology

D Xu, K Di, B Fan, J Wu, X Gu, Y Sun… - … in Bioengineering and …, 2022 - frontiersin.org
MicroRNAs (miRNAs) are a class of short, single-stranded, noncoding RNAs, with a length
of about 18–22 nucleotides. Extracellular vesicles (EVs) are derived from cells and play a …

[HTML][HTML] Exosomal proteins and lipids as potential biomarkers for lung cancer diagnosis, prognosis, and treatment

MT Hsu, YK Wang, YJ Tseng - Cancers, 2022 - mdpi.com
Simple Summary Exosomes (or extracellular vesicles) are known to mediate intercellular
communication and to transmit molecular signals between cells. Molecules carried by …

[HTML][HTML] The role of exosomes in lung cancer metastasis and clinical applications: an updated review

L Yin, X Liu, X Shao, T Feng, J Xu, Q Wang… - Journal of Translational …, 2021 - Springer
Lung cancer is the leading cause of cancer-associated deaths accounting for 24% of all
cancer deaths. As a crucial phase of tumor progression, lung cancer metastasis is linked to …

[HTML][HTML] The role of circulating biomarkers in lung cancer

S Herath, H Sadeghi Rad, P Radfar, R Ladwa… - Frontiers in …, 2022 - frontiersin.org
Lung cancer is the leading cause of cancer morbidity and mortality worldwide and early
diagnosis is crucial for the management and treatment of this disease. Non-invasive means …

DNA barcode-based detection of exosomal microRNAs using nucleic acid lateral flow assays for the diagnosis of colorectal cancer

S Kim, J Han, JS Park, JH Kim, ES Lee, BS Cha… - Talanta, 2022 - Elsevier
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
cancer-related deaths worldwide. The standard methods for diagnosing CRC, endoscopy …