Hydrogel‐based growth factor delivery platforms: strategies and recent advances

BH Shan, FG Wu - Advanced Materials, 2024 - Wiley Online Library
Growth factors play a crucial role in regulating a broad variety of biological processes and
are regarded as powerful therapeutic agents in tissue engineering and regenerative …

Development of innovative biomaterials and devices for the treatment of cardiovascular diseases

Y Wang, G Li, L Yang, R Luo, G Guo - Advanced Materials, 2022 - Wiley Online Library
Cardiovascular diseases have become the leading cause of death worldwide. The
increasing burden of cardiovascular diseases has become a major public health problem …

[HTML][HTML] Current understanding of hydrogel for drug release and tissue engineering

L Lei, Y Bai, X Qin, J Liu, W Huang, Q Lv - Gels, 2022 - mdpi.com
Due to their good absorption, satisfactory biocompatibility, and high safety, hydrogels have
been widely used in the field of biomedicine, including for drug delivery and tissue …

Microneedle patch loaded with exosomes containing microRNA‐29b prevents cardiac fibrosis after myocardial infarction

J Yuan, H Yang, C Liu, L Shao, H Zhang… - Advanced …, 2023 - Wiley Online Library
Myocardial infarction (MI) is a cardiovascular disease that poses a serious threat to human
health. Uncontrolled and excessive cardiac fibrosis after MI has been recognized as a …

Injectable multifunctional chitosan/dextran-based hydrogel accelerates wound healing in combined radiation and burn injury

J Shen, W Jiao, Z Chen, C Wang, X Song, L Ma… - Carbohydrate …, 2023 - Elsevier
Clinical wound management of combined radiation and burn injury (CRBI) remains a huge
challenge due to serious injuries induced by redundant reactive oxygen species (ROS), the …

Advances in injectable hydrogel strategies for heart failure treatment

S He, Z Zhang, R Luo, Q Jiang, L Yang… - Advanced Healthcare …, 2023 - Wiley Online Library
Heart failure (HF) affects 60 million people worldwide and has developed into a global
public health problem surpassing cancer and urgently needs to be solved. According to the …

A ROS‐Responsive Liposomal Composite Hydrogel Integrating Improved Mitochondrial Function and Pro‐Angiogenesis for Efficient Treatment of Myocardial …

Z Zheng, C Lei, H Liu, M Jiang, Z Zhou… - Advanced …, 2022 - Wiley Online Library
Mitochondrial dysfunction of cardiomyocytes (CMs) has been identified as a significant
pathogenesis of early myocardial infarction (MI). However, only a few agents or strategies …

[HTML][HTML] An injectable conductive hydrogel with dual responsive release of rosmarinic acid improves cardiac function and promotes repair after myocardial infarction

L Zhang, Z Bei, T Li, Z Qian - Bioactive Materials, 2023 - Elsevier
Myocardial infarction (MI) causes irreversible damage to the heart muscle, seriously
threatening the lives of patients. Injectable hydrogels have attracted extensive attention in …

Injectable decellularized extracellular matrix hydrogel containing stromal cell-derived factor 1 promotes transplanted cardiomyocyte engraftment and functional …

K Wu, Y Wang, H Yang, Y Chen, K Lu… - … Applied Materials & …, 2023 - ACS Publications
Transplantation of exogenous cardiomyocytes (CMs) is a hopeful method to treat myocardial
infarction (MI). However, its clinical application still remains challenging due to low retention …

Self-assembly hydrogels of therapeutic agents for local drug delivery

J Zheng, X Song, Z Yang, C Yin, W Luo, C Yin… - Journal of Controlled …, 2022 - Elsevier
Advanced drug delivery systems are of vital importance to enhance therapeutic efficacy.
Among various recently developed formulations, self-assembling hydrogels composed of …