Tryptophan biochemistry: structural, nutritional, metabolic, and medical aspects in humans
L Palego, L Betti, A Rossi… - Journal of amino …, 2016 - Wiley Online Library
L‐Tryptophan is the unique protein amino acid (AA) bearing an indole ring: its
biotransformation in living organisms contributes either to keeping this chemical group in …
biotransformation in living organisms contributes either to keeping this chemical group in …
Bright-light therapy in the treatment of mood disorders
G Pail, W Huf, E Pjrek, D Winkler, M Willeit… - …, 2011 - karger.com
Bright-light therapy (BLT) is established as the treatment of choice for seasonal affective
disorder/winter type (SAD). In the last two decades, the use of BLT has expanded beyond …
disorder/winter type (SAD). In the last two decades, the use of BLT has expanded beyond …
Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application
MJ Millan - Pharmacology & therapeutics, 2006 - Elsevier
Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …
high social cost. Depressed patients generally display co-morbid symptoms, and depression …
The role of serotonin in human mood and social interaction: insight from altered tryptophan levels
Alterations in brain tryptophan levels cause changes in brain serotonin synthesis, and this
has been used to study the implication of altered serotonin levels in humans. In the acute …
has been used to study the implication of altered serotonin levels in humans. In the acute …
Sleep deprivation in depression: what do we know, where do we go?
A Wirz-Justice, RH Van den Hoofdakker - Biological psychiatry, 1999 - Elsevier
Manipulations of the sleep-wake cycle, whether of duration (total or partial sleep deprivation
[SD]) or timing (partial SD, phase advance), have profound and rapid effects on depressed …
[SD]) or timing (partial SD, phase advance), have profound and rapid effects on depressed …
Therapeutic use of sleep deprivation in depression
H Giedke, F Schwärzler - Sleep medicine reviews, 2002 - Elsevier
Total sleep deprivation (TSD) for one whole night improves depressive symptoms in 40–
60% of treatments. The degree of clinical change spans a continuum from complete …
60% of treatments. The degree of clinical change spans a continuum from complete …
Prediction of antidepressant effects of sleep deprivation by metabolic rates in the ventral anterior cingulate and medial prefrontal cortex
J Wu, MS Buchsbaum, JC Gillin… - American Journal of …, 1999 - Am Psychiatric Assoc
OBJECTIVE: Sleep deprivation has been shown to have an antidepressant benefit in a
subgroup of depressed patients. Functional imaging studies by the authors and others have …
subgroup of depressed patients. Functional imaging studies by the authors and others have …
The role of noradrenaline and selective noradrenaline reuptake inhibition in depression
N Brunello, J Mendlewicz, S Kasper, B Leonard… - European …, 2002 - Elsevier
Depression is a common disorder that impacts on all aspects of a person's life. For the past
10 years, clinicians have focused on serotonin in their treatment of depression. This is …
10 years, clinicians have focused on serotonin in their treatment of depression. This is …
Chronotherapeutics in a psychiatric ward
F Benedetti, B Barbini, C Colombo, E Smeraldi - Sleep medicine reviews, 2007 - Elsevier
Psychiatric chronotherapeutics is the controlled exposure to environmental stimuli that act
on biological rhythms in order to achieve therapeutic effects in the treatment of psychiatric …
on biological rhythms in order to achieve therapeutic effects in the treatment of psychiatric …
Clinical and physiological consequences of rapid tryptophan depletion
P Moore, HP Landolt, E Seifritz, C Clark, T Bhatti… - …, 2000 - Elsevier
We review here the rapid tryptophan depletion (RTD) methodology and its controversial
association with depressive relapse. RTD has been used over the past decade to deplete …
association with depressive relapse. RTD has been used over the past decade to deplete …