Heterocycles are an important class of organic compounds accounting for nearly one-third of
the past decade's publications, which are in the field of heterocyclic chemistry. In fact, two …

While natural products have undoubtedly played a pivotal role in drug discovery, their
potential as lead compounds has been hindered by challenges such as limited accessibility …

A photocatalytic process for 1, 7-enyne bicyclizations with α-bromo diethyl malonate has
been established via synergistic domino bicyclizations. This protocol provides an efficient …

Indole alkaloids are an important group of natural products in the plant kingdom for their
diversity structures and significant biological effects on human health. The genus Melodinus …

Abstract Melodinus cochinchinensis (Lour.) Merr. has been used in Traditional Chinese
Medicine for the management of various ailments, yet its chemical constituents are rarely …

Meloyunnanines A–C, three alkaloids with an unprecedented skeleton, were isolated from
fruits of Melodinus yunnanensis. The structures featuring a caged-6/6/5/6/5/5 ring system …

Six new structurally diverse indole alkaloids, melohemsines J–M (1–4), 11-hydroxy-Δ14-
vincamine (5), and 11-hydroxy-16-epi-Δ14-vincamine (6), and 15 known alkaloids were …

Melodinus is an important genus comprising of approximately 53 species of medicinal plants
(Apocynaceae). Some species have been used in Chinese folk medicine for the treatment of …

Plant seeds are a renewable resource that can furnish access to medicinal natural products
that can only otherwise be isolated from aerial or root parts, the harvest of which may be …

Nine new melodinus-type alkaloids, melohemsines AI (1–9), together with eight known ones
were isolated from Melodinus hemselyanus. The structures of the new alkaloids, including …