Red blood cells (RBCs) are a specialised organ that enabled the evolution of multicellular
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …

Red blood cell (RBC) aging in the blood bank is characterized by the accumulation of a
significant number of biochemical and morphologic alterations. Recent mass spectrometry …

Background Some observational studies have reported that transfusion of red-cell units that
have been stored for more than 2 to 3 weeks is associated with serious, even fatal, adverse …

Red blood cell (RBC) storage in the blood bank promotes the progressive accumulation of
metabolic alterations that may ultimately impact the erythrocyte capacity to cope with oxidant …

Capillary blood vessels, the smallest vessels in the body, form an intricate network with
constantly bifurcating, merging and winding vessels. Red blood cells (RBCs) must navigate …

Hemorrhagic shock (HS) management is based on a timely, rapid, definitive source control
of bleeding/s and on blood loss replacement. Stopping the hemorrhage from progressing …

Red blood cell transfusion is a life-saving intervention, and storage is a logistic necessity to
make~ 110 million units available for transfusion every year worldwide. However, storage in …

BACKGROUND: Erythrocyte cell membranes undergo morphologic changes during storage,
but it is unclear whether these changes are reversible. We assessed erythrocyte cell …

The objective of this paper is to introduce clinicians and health care professionals to the
concept of patient blood management (PBM) and to explain the difference between PBM …

BACKGROUND Being devoid of de novo protein synthesis capacity, red blood cells (RBCs)
have evolved to recycle oxidatively damaged proteins via mechanisms that involve …