Burns are a seriously underestimated form of trauma that not only damage the skin system
but also cause various complications, such as acute kidney injury (AKI). Recent clinical …

Acute kidney injury (AKI) is a major clinical problem associated with increased morbidity and
mortality. Despite intensive research, the clinical outcome remains poor, and apart from …

Acute kidney injuries (AKI) have serious short-term or long-term complications with high
morbidity and mortality rate, thus posing great health threats. Developing high-performance …

Background AKI triggers a proliferative response as part of an intrinsic cellular repair
program, which can lead to adaptive renal repair, restoring kidney structure and function, or …

Mononuclear phagocytes (MP), ie, monocytes, macrophages, and dendritic cells (DCs), are
essential for immune homeostasis via their capacities to clear pathogens, pathogen …

Near-infrared dyes have attracted widespread attention due to their intense absorption and
emission in the near-infrared region. As an important class of heteroatom-containing …

Background The NLRP3 inflammasome integrates several danger signals into the activation
of innate immunity and inflammation by secreting IL-1β and IL-18. Most published data …

ABSTRACT A characteristic of normal aging and age-related diseases is the remodeling of
the cellular organization of a tissue through polyploid cell growth. Polyploidy arises from an …

A pervasive view is that undifferentiated stem cells are alone responsible for generating all
other cells and are the origins of cancer. However, emerging evidence demonstrates fully …

Acute kidney injury (AKI)-to-chronic kidney disease (CKD) transition is a slow but persistent
progression toward end-stage kidney disease. Earlier reports have shown that Hippo …