Integrating the overlap of obstructive lung disease and obstructive sleep apnoea: OLDOSA syndrome

OC Ioachimescu, M Teodorescu - Respirology, 2013 - Wiley Online Library
Obstructive lung diseases (OLD) such as asthma and chronic obstructive pulmonary disease
(COPD) are very prevalent conditions. Disease phenotypes (eg chronic bronchitis …

The effect of azithromycin in adults with stable neutrophilic COPD: a double blind randomised, placebo controlled trial

JL Simpson, H Powell, KJ Baines, D Milne, HO Coxson… - PloS one, 2014 - journals.plos.org
Background Chronic Obstructive Pulmonary Disease (COPD) is a progressive airway
disease characterised by neutrophilic airway inflammation or bronchitis. Neutrophilic …

Airway microbiome-immune crosstalk in chronic obstructive pulmonary disease

A Kayongo, NM Robertson, T Siddharthan… - Frontiers in …, 2023 - frontiersin.org
Chronic Obstructive Pulmonary Disease (COPD) has significantly contributed to global
mortality, with three million deaths reported annually. This impact is expected to increase …

Consensus document on the diagnosis and treatment of chronic bronchial infection in chronic obstructive pulmonary disease

D de la Rosa Carrillo, JL López-Campos… - Archivos de …, 2020 - Elsevier
Although the chronic presence of microorganisms in the airways of patients with stable
chronic obstructive pulmonary disease (COPD) confers a poor outcome, no …

Potentially pathogenic bacteria cultured from the sputum of stable asthmatics are associated with increased 8-isoprostane and airway neutrophilia

LG Wood, JL Simpson, PM Hansbro… - Free radical …, 2010 - Taylor & Francis
Potential bacterial pathogens are found in the airways in several diseases that are
associated with neutrophilic inflammation. The aim of this study was to characterize subjects …

Chronic bronchial infection is associated with more rapid lung function decline in chronic obstructive pulmonary disease

MÁ Martínez-García, R Faner, G Oscullo… - Annals of the …, 2022 - atsjournals.org
Rationale: Some patients with chronic obstructive pulmonary disease (COPD) suffer
accelerated lung function (forced expiratory volume in 1 second [FEV1]) decline over time …

Aging with HIV in the ART era

E Kaplan-Lewis, JA Aberg, M Lee - Seminars in diagnostic pathology, 2017 - Elsevier
In the current era of therapy for human immunodeficiency virus (HIV), life expectancy for
persons living with HIV (PLWH) approaches that of the general population. This newly …

Neutrophilic inflammation in the pathogenesis of chronic obstructive pulmonary disease

A Butler, GM Walton, E Sapey - COPD: Journal of Chronic …, 2018 - Taylor & Francis
Current paradigms of chronic obstructive pulmonary disease (COPD) treatment suggest
stratifying patients by their symptoms, utilising three main drug classes, but it is unclear if this …

Relationships among bacteria, upper airway, lower airway, and systemic inflammation in COPD

JR Hurst, TMA Wilkinson, WR Perera, GC Donaldson… - Chest, 2005 - Elsevier
Study objective The upper and lower airways are continuous. While upper airway symptoms
are common in COPD patients, with accumulating evidence to suggest increased nasal …

[HTML][HTML] Antibiotics for treatment and prevention of exacerbations of chronic obstructive pulmonary disease

R Wilson, S Sethi, A Anzueto, M Miravitlles - Journal of Infection, 2013 - Elsevier
Acute exacerbations (AE) can be recurrent problems for patients with moderate-to-severe
chronic obstructive pulmonary disease (COPD) increasing morbidity and mortality. Evidence …