Involvement of the innate immune system in the pathogenesis of chronic obstructive pulmonary disease

S Kotlyarov - International Journal of Molecular Sciences, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a common, socially significant disease
characterized by progressive airflow limitation due to chronic inflammation in the bronchi …

Moraxella catarrhalis is internalized in respiratory epithelial cells by a trigger‐like mechanism and initiates a TLR2‐ and partly NOD1‐dependent inflammatory …

H Slevogt, J Seybold, KN Tiwari, AC Hocke… - Cellular …, 2007 - Wiley Online Library
Moraxella catarrhalis is an important pathogen in patients with chronic obstructive lung
disease (COPD). While M. catarrhalis has been categorized as an extracellular bacterium so …

[图书][B] An atlas of chronic obstructive pulmonary disease

TT Hansel, PJ Barnes - 2003 - taylorfrancis.com
Despite being the most common respiratory disorder in the developed world and the fourth
leading cause of death in the US, chronic obstructive pulmonary disease (COPD) has …

Systemic Inflammation in Patients with Chronic Obstructive Pulmonary Disease Who Are Colonized with Pneumocystis jiroveci

EJ Calderón, L Rivero, N Respaldiza… - Clinical Infectious …, 2007 - academic.oup.com
In chronic obstructive pulmonary disease, high levels of airway and systemic inflammatory
markers are associated with a faster decrease in lung function. Our study shows that patients …

Genetic determinants of emphysema distribution in the national emphysema treatment trial

DL DeMeo, CP Hersh, EA Hoffman… - American journal of …, 2007 - atsjournals.org
Rationale: Computed tomography (CT) scanning of the lung may reduce phenotypic
heterogeneity in defining subjects with chronic obstructive pulmonary disease (COPD), and …

Chronic respiratory infection in patients with chronic obstructive pulmonary disease: what is the role of antibiotics?

M Miravitlles, A Anzueto - International journal of molecular sciences, 2017 - mdpi.com
Chronic infections are associated with exacerbation in patients with chronic obstructive
pulmonary disease (COPD). The major objective of the management of these patients is the …

Variability and effects of bronchial colonisation in patients with moderate COPD

A Marin, E Monsó, M Garcia-Nunez… - European …, 2010 - Eur Respiratory Soc
Sputum and lung function were periodically assessed in stable moderate chronic obstructive
pulmonary disease (COPD) outpatients to determine relationships between bronchial …

Bronchial infection and temporal evolution of bronchiectasis in patients with chronic obstructive pulmonary disease

MÁ Martínez-García… - Clinical Infectious …, 2021 - academic.oup.com
Background Bronchiectasis (BE) impact the clinical course and prognosis of patients with
chronic obstructive pulmonary disease (COPD). Yet, the temporal evolution of BE in these …

Role of neutrophils in mucus hypersecretion in COPD and implications for therapy

S Kim, JA Nadel - Treatments in respiratory medicine, 2004 - Springer
Airway mucus hypersecretion is a serious and presently untreatable symptom of COPD.
Over the past several years, emerging evidence has implicated epidermal growth factor …

Periodontitis aggravates COPD through the activation of γδ T cell and M2 macrophage

K Xiong, K Ao, W Wei, J Dong, J Li, Y Yang, B Tang… - Msystems, 2024 - Am Soc Microbiol
Chronic obstructive pulmonary disease (COPD) is a chronic systemic inflammatory disease
with high morbidity and mortality. Periodontitis exacerbates COPD progression; however …