Modelling extravascular drug penetration using multilayered cell cultures
AH Kyle - 1999 - open.library.ubc.ca
This thesis describes experiments using multilayered cell cultures (MCCs) to examine the
ability of anticancer drugs to penetrate the extravascular compartment of tumour tissue. An …
ability of anticancer drugs to penetrate the extravascular compartment of tumour tissue. An …
Cultivation of mammalian cells in heat-sealable pouches that are permeable to carbon dioxide
RJ Klebe, S Lyn, VL Magnuson, G Zardeneta - Experimental Cell Research, 1990 - Elsevier
Abstract Petri plates, 96-well plates, and other unsealed culture vessels are the chief cause
of air-borne contamination of cell cultures. In this study, heat-sealable plastic pouches that …
of air-borne contamination of cell cultures. In this study, heat-sealable plastic pouches that …
[图书][B] Control and optimization of electroporation-mediated drug and gene delivery
PJ Canatella - 2000 - search.proquest.com
Electroporation has been shown to be an effective method to temporarily disrupt cellular
membranes and other biological barriers and thereby enhance gene delivery and clinical …
membranes and other biological barriers and thereby enhance gene delivery and clinical …
[图书][B] Tumor microenvironmental conditions involved in host/tumor cell interactions
ML Woods - 1996 - search.proquest.com
Conditions within the tumor microenvironment, including cytokines and low oxygen levels,
affect the interaction of host immune cells with tumor. The effect of these factors was studied …
affect the interaction of host immune cells with tumor. The effect of these factors was studied …
[图书][B] Comparative analysis of a two-dimensional and three-dimensional model of BT-20 triple negative breast carcinoma cells in response to an antiproliferative …
J Wang - 2018 - search.proquest.com
Triple-negative breast cancer (TNBC) lacks the expression of estrogen receptor-alpha,
progesterone receptor and human epidermal growth factor receptor 2 (HER2). The lack of …
progesterone receptor and human epidermal growth factor receptor 2 (HER2). The lack of …
[引用][C] Multicellular tumor spheroids: intermediates between monolayer culture and in vivo tumor
LA Kunz-Schughart - Cell biology international, 1999 - Elsevier
Pioneered by the work of two developmental biologists, J. Holtfreter and A. Moscona, in the
1940s and 1950s, the methodology of cell aggregates was adapted to cancer research by …
1940s and 1950s, the methodology of cell aggregates was adapted to cancer research by …