The role of the innate and adaptive immune system in pediatric inflammatory bowel disease

LA Denson - Inflammatory bowel diseases, 2013 - academic.oup.com
Recent translational studies have provided new insights into the pathogenesis of pediatric-
onset inflammatory bowel disease. Registry studies have identified distinct clinical …

Genetic susceptibility and genotype–phenotype association in 588 Danish children with inflammatory bowel disease

C Jakobsen, I Cleynen, PS Andersen… - Journal of Crohn's …, 2014 - academic.oup.com
Aim To investigate the association between known inflammatory bowel disease (IBD)-
associated genetic variants and development of paediatric IBD, and specific clinical sub …

Evolution of disease phenotype in pediatric-onset Crohn's disease after more than 10 years follow up—Cohort study

F Rinawi, A Assa, C Hartman, YM Glassberg… - Digestive and Liver …, 2016 - Elsevier
Abstract Background Pediatric-onset Crohn's disease (CD) is a heterogeneous disorder
which is subjected to progression and complications in a substantial proportion of patients …

A promising natural killer cell-based model and a nomogram for the prognostic prediction of clear-cell renal cell carcinoma

Q Yao, X Zhang, Y Wang, C Wang, J Chen… - European Journal of …, 2024 - Springer
Background Clear-cell renal cell carcinoma (ccRCC) is one of prevalent kidney
malignancies with an unfavorable prognosis. There is a need for a robust model to predict …

[HTML][HTML] Living with inflammatory bowel disease: protocol for a longitudinal study of factors associated with symptom exacerbations

K Witges, LE Targownik, C Haviva… - JMIR research …, 2018 - researchprotocols.org
Background There has been limited longitudinal research that has comprehensively
evaluated possible factors in the exacerbation of inflammatory bowel disease (IBD) …

Predicting outcomes in acute severe ulcerative colitis

NT Ventham, R Kalla, NA Kennedy… - Expert review of …, 2015 - Taylor & Francis
Response to corticosteroid treatment in acute severe ulcerative colitis (ASUC) has changed
very little in the past 50 years. Predicting those at risk at an early stage helps stratify patients …

Small bowel Crohn's disease: an emerging disease phenotype?

B Hall, G Holleran, D McNamara - Digestive Diseases, 2014 - karger.com
An increasing understanding of the pathogenesis of Crohn's disease (CD), coupled with
improvements in therapeutic options, has promoted the concept of stratifying patients with …

Autoantibodies against glycoprotein 2 isoforms in pediatric patients with inflammatory bowel disease

N Röber, L Noß, A Goihl, D Reinhold… - Inflammatory bowel …, 2017 - academic.oup.com
Background Anti-Glycoprotein 2 (GP2) antibodies are associated with a more complicated
course of Crohn's disease (CD) in adults. Four different GP2 isoforms with different length …

Combining TNFSF 15 and ASCA IgA can be used as a predictor for the stenosis/perforating phenotype of C rohn's disease

CC Tung, JM Wong, WC Lee, HH Liu… - Journal of …, 2014 - Wiley Online Library
Abstract Background and Aim Focusing on TNFSF 15 instead of NOD 2, we set out to
evaluate whether combining serologic and genetic markers could distinguish between …

Are we ready to include prognostic factors in inflammatory bowel disease trials?

CR Lindholm, CA Siegel - Current Pharmaceutical Design, 2019 - ingentaconnect.com
Inflammatory bowel disease (IBD) is a chronic inflammatory disease characterized by
periodic episodes of flares and remission. Treatment is aimed at healing the bowel, to …