Role of sleep deprivation in immune-related disease risk and outcomes

S Garbarino, P Lanteri, NL Bragazzi… - Communications …, 2021 - nature.com
Modern societies are experiencing an increasing trend of reduced sleep duration, with
nocturnal sleeping time below the recommended ranges for health. Epidemiological and …

The sleep-immune crosstalk in health and disease

L Besedovsky, T Lange, M Haack - Physiological reviews, 2019 - journals.physiology.org
Sleep-immune interactions are well-known phenomena in everyday life and folk wisdom.
There is no doubt that an infection makes us tired and increases the desire to sleep, and a …

Rising temperatures erode human sleep globally

K Minor, A Bjerre-Nielsen, SS Jonasdottir, S Lehmann… - One Earth, 2022 - cell.com
Ambient temperatures are rising worldwide, with the greatest increases recorded at night.
Concurrently, the prevalence of insufficient sleep is rising in many populations. Yet it …

Crosstalk between metabolism and circadian clocks

H Reinke, G Asher - Nature Reviews Molecular Cell Biology, 2019 - nature.com
Humans, like all mammals, partition their daily behaviour into activity (wakefulness) and rest
(sleep) phases that differ largely in their metabolic requirements. The circadian clock …

Sleep deprivation and stress: a reciprocal relationship

M Nollet, W Wisden, NP Franks - Interface focus, 2020 - royalsocietypublishing.org
Sleep is highly conserved across evolution, suggesting vital biological functions that are yet
to be fully understood. Animals and humans experiencing partial sleep restriction usually …

Oscillating circuitries in the sleeping brain

AR Adamantidis, C Gutierrez Herrera… - Nature Reviews …, 2019 - nature.com
Brain activity during sleep is characterized by circuit-specific oscillations, including slow
waves, spindles and theta waves, which are nested in thalamocortical or hippocampal …

Microbiota and sleep: awakening the gut feeling

P Sen, A Molinero-Perez, KJ O'Riordan… - Trends in molecular …, 2021 - cell.com
Various lifestyle and environmental factors are known to influence sleep. Increasingly,
evidence points to a role for the microbiota in regulating brain and behaviour. This article …

Role of sleep and circadian disruption on energy expenditure and in metabolic predisposition to human obesity and metabolic disease

AW McHill, KP Wright Jr - Obesity reviews, 2017 - Wiley Online Library
Weight gain, obesity and diabetes have reached alarming levels in the developed world.
Traditional risk factors such as over‐eating, poor nutritional choices and lack of exercise …

What is REM sleep?

MS Blumberg, JA Lesku, PA Libourel, MH Schmidt… - Current biology, 2020 - cell.com
For many decades, sleep researchers have sought to determine which species 'have'rapid
eye movement (REM) sleep. In doing so, they relied predominantly on a template derived …

Evidence that birds sleep in mid-flight

NC Rattenborg, B Voirin, SM Cruz, R Tisdale… - Nature …, 2016 - nature.com
Many birds fly non-stop for days or longer, but do they sleep in flight and if so, how? It is
commonly assumed that flying birds maintain environmental awareness and aerodynamic …