[HTML][HTML] Linking the Amyloid, Tau, and Mitochondrial Hypotheses of Alzheimer's Disease and Identifying Promising Drug Targets
Z Fišar - Biomolecules, 2022 - mdpi.com
Damage or loss of brain cells and impaired neurochemistry, neurogenesis, and synaptic and
nonsynaptic plasticity of the brain lead to dementia in neurodegenerative diseases, such as …
nonsynaptic plasticity of the brain lead to dementia in neurodegenerative diseases, such as …
[HTML][HTML] New strategies of neurodegenerative disease treatment with extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs)
CP Palanisamy, JJ Pei, P Alugoju, NVA Anthikapalli… - Theranostics, 2023 - ncbi.nlm.nih.gov
Neurodegenerative diseases are characterized by the progressive loss of neurons and
intricate interactions between different cell types within the affected regions. Reliable …
intricate interactions between different cell types within the affected regions. Reliable …
Matrine-induced nephrotoxicity via GSK-3β/nrf2-mediated mitochondria-dependent apoptosis
T Wang, J Zhang, H Wei, X Wang, M Xie, Y Jiang… - Chemico-Biological …, 2023 - Elsevier
Introduction Matrine (MT), an ingredient extracted from the Chinese herb Sophora
flavescens, can result in nephrotoxicity because of long-term exposure. However, the …
flavescens, can result in nephrotoxicity because of long-term exposure. However, the …
[HTML][HTML] Therapeutic potential of targeting mitochondria for Alzheimer's disease treatment
Alzheimer's disease (AD), a chronic and progressive neurodegenerative disease, is
characterized by memory and cognitive impairment and by the accumulation in the brain of …
characterized by memory and cognitive impairment and by the accumulation in the brain of …
[PDF][PDF] Transcriptome analysis identifies the role of Class I histone deacetylase in Alzheimer's disease
F Geng, N Zhao, X Chen, XT Liu, MM Zhu, Y Jiang… - Heliyon, 2023 - cell.com
Epigenetics modification is a process that does not change the sequence of
deoxyribonucleic acid (DNA) in disease progression but can alter the genetic expression of …
deoxyribonucleic acid (DNA) in disease progression but can alter the genetic expression of …
[HTML][HTML] Ketogenic diet alleviates cognitive dysfunction and neuroinflammation in APP/PS1 mice via the Nrf2/HO-1 and NF-κB signaling pathways
J Jiang, H Pan, F Shen, Y Tan… - Neural Regeneration …, 2023 - journals.lww.com
Alzheimer's disease is a progressive neurological disorder characterized by cognitive
decline and chronic inflammation within the brain. The ketogenic diet, a widely recognized …
decline and chronic inflammation within the brain. The ketogenic diet, a widely recognized …
Multifaceted roles of mitochondrial dysfunction in diseases: from powerhouses to saboteurs
SS Prabhu, AS Nair, SV Nirmala - Archives of Pharmacal Research, 2023 - Springer
The fact that mitochondria play a crucial part in energy generation has led to the nickname
“powerhouses” of the cell being applied to them. They also play a significant role in many …
“powerhouses” of the cell being applied to them. They also play a significant role in many …
Fabrication and characterization of Hypecoum pendulum‐assisted novel bio‐inspired silver nanoparticles and their antioxidant, anti‐diabetic, and anti‐Alzheimer …
NU Huda, M Ahmed, N Mushtaq… - Applied Organometallic …, 2023 - Wiley Online Library
This research aims to study the biogenic synthesis and characterization of Hypecoum
pendulum extract‐induced silver nanoparticles (HP‐AgNPs) and to investigate its …
pendulum extract‐induced silver nanoparticles (HP‐AgNPs) and to investigate its …
Understanding the mechanisms of disease modifying effects of aerobic exercise in people with Alzheimer's disease
A Abdullahi, TWL Wong, SSM Ng - Ageing Research Reviews, 2024 - Elsevier
Alzheimer's disease (AD) is a very disabling disease. Pathologically, it is characterized by
the presence of amyloid plaques and neurofibrillary tangles in the brain that results in …
the presence of amyloid plaques and neurofibrillary tangles in the brain that results in …
[HTML][HTML] Mitochondrial Complex I and β-Amyloid Peptide Interplay in Alzheimer's Disease: A Critical Review of New and Old Little Regarded Findings
Alzheimer's disease (AD) is the most common neurodegenerative disorder and the main
cause of dementia which is characterized by a progressive cognitive decline that severely …
cause of dementia which is characterized by a progressive cognitive decline that severely …