[HTML][HTML] The use of iron oxide nanoparticles to reprogram macrophage responses and the immunological tumor microenvironment

V Mulens-Arias, JM Rojas, DF Barber - Frontiers in immunology, 2021 - frontiersin.org
The synthesis and functionalization of iron oxide nanoparticles (IONPs) is versatile, which
has enhanced the interest in studying them as theranostic agents over recent years. As …

Iron oxide nanoparticles for immune cell labeling and cancer immunotherapy

S Chung, RA Revia, M Zhang - Nanoscale horizons, 2021 - pubs.rsc.org
Cancer immunotherapy is a novel approach to cancer treatment that leverages components
of the immune system as opposed to chemotherapeutics or radiation. Cell migration is an …

Interaction of iron oxide nanoparticles with macrophages is influenced distinctly by “self” and “non-self” biological identities

Y Portilla, V Mulens-Arias, N Daviu… - … Applied Materials & …, 2023 - ACS Publications
Upon contact with biological fluids like serum, a protein corona (PC) complex forms on iron
oxide nanoparticles (IONPs) in physiological environments and the proteins it contains …

New facets of nanozyme activity of ceria: Lipo-and phospholipoperoxidase-like behaviour of CeO 2 nanoparticles

MM Sozarukova, EV Proskurnina, AL Popov… - RSC …, 2021 - pubs.rsc.org
Cerium dioxide nanoparticles have a special place among engineered nanomaterials due to
the wide range of their enzyme-like activities. They possess SOD-, catalase-and peroxidase …

Understanding the phagocytosis of particles: the key for rational design of vaccines and therapeutics

S Moreno-Mendieta, D Guillén… - Pharmaceutical …, 2022 - Springer
A robust comprehension of phagocytosis is crucial for understanding its importance in innate
immunity. A detailed description of the molecular mechanisms that lead to the uptake and …

The intrinsic biological identities of iron oxide nanoparticles and their coatings: unexplored territory for combinatorial therapies

V Mulens-Arias, JM Rojas, DF Barber - Nanomaterials, 2020 - mdpi.com
Over the last 20 years, iron oxide nanoparticles (IONPs) have been the subject of increasing
investigation due to their potential use as theranostic agents. Their unique physical …

Immunotoxic effects of metal-based nanoparticles in fish and bivalves

S Rastgar, R Alijani Ardeshir, H Segner, CR Tyler… - …, 2022 - Taylor & Francis
There is a global research interest in metal nanoparticles (MNPs) due to their diverse
applications, rapidly increasing use, and increased presence in the aquatic environment …

[HTML][HTML] Engineering Macrophages via Nanotechnology and Genetic Manipulation for Cancer Therapy

X Ding, X Sun, H Cai, L Wu, Y Liu, Y Zhao… - Frontiers in …, 2022 - frontiersin.org
Macrophages play critical roles in tumor progression. In the tumor microenvironment,
macrophages display highly diverse phenotypes and may perform antitumorigenic or …

The influence of IONPs core size on their biocompatibility and activity in in vitro cellular models

N Janik-Olchawa, A Drozdz, D Ryszawy, M Pudelek… - Scientific Reports, 2021 - nature.com
Although the key factor affecting the biocompatibility of IONPs is the core size, there is a lack
of regular investigation concerning the impact of the parameter on the toxicity of these …

Adverse Responses following Exposure to Subtoxic Concentrations of Zinc Oxide and Nickle Oxide Nanoparticles in the Raw 264.7 Cells

NB Alsaleh, MA Assiri, AM Aljarbou, MM Almutairi… - Toxics, 2023 - mdpi.com
The incorporation of engineered nanomaterials (ENMs) in biomedical and consumer
products has been growing, leading to increased human exposure. Previous research was …