Acute heart failure

M Arrigo, M Jessup, W Mullens, N Reza… - Nature Reviews …, 2020 - nature.com
Acute heart failure (AHF) is a syndrome defined as the new onset (de novo heart failure
(HF)) or worsening (acutely decompensated heart failure (ADHF)) of symptoms and signs of …

[HTML][HTML] Cardiac macrophage biology in the steady-state heart, the aging heart, and following myocardial infarction

Y Ma, AJ Mouton, ML Lindsey - Translational Research, 2018 - Elsevier
Macrophages play critical roles in homeostatic maintenance of the myocardium under
normal conditions and in tissue repair after injury. In the steady-state heart, resident cardiac …

Targeting age-related pathways in heart failure

H Li, MH Hastings, J Rhee, LE Trager, JD Roh… - Circulation …, 2020 - Am Heart Assoc
During aging, deterioration in cardiac structure and function leads to increased susceptibility
to heart failure. The need for interventions to combat this age-related cardiac decline is …

The impact of aging on cardiac extracellular matrix

CA Meschiari, OK Ero, H Pan, T Finkel, ML Lindsey - Geroscience, 2017 - Springer
Age-related changes in cardiac homeostasis can be observed at the cellular, extracellular,
and tissue levels. Progressive cardiomyocyte hypertrophy, inflammation, and the gradual …

So! What's aging? Is cardiovascular aging a disease?

EG Lakatta - Journal of molecular and cellular cardiology, 2015 - Elsevier
Abstract “Inside every old person is a young person wondering what happened.” So, what is
aging? Aging is a manifestation of progressive, time-dependent failure of molecular …

The effect of cytokines on osteoblasts and osteoclasts in bone remodeling in osteoporosis: A review

J Xu, L Yu, F Liu, L Wan, Z Deng - Frontiers in Immunology, 2023 - frontiersin.org
The complicated connections and cross talk between the skeletal system and the immune
system are attracting more attention, which is developing into the field of Osteoimmunology …

Cardiac ageing: extrinsic and intrinsic factors in cellular renewal and senescence

NA Gude, KM Broughton, F Firouzi… - Nature Reviews …, 2018 - nature.com
Cardiac ageing manifests as a decline in function leading to heart failure. At the cellular
level, ageing entails decreased replicative capacity and dysregulation of cellular processes …

The role of oxidative stress in the aging heart

LU Pagan, MJ Gomes, M Gatto, GAF Mota, K Okoshi… - Antioxidants, 2022 - mdpi.com
Medical advances and the availability of diagnostic tools have considerably increased life
expectancy and, consequently, the elderly segment of the world population. As age is a …

Chronic low‐grade inflammation in heart failure with preserved ejection fraction

T Mesquita, YN Lin, A Ibrahim - Aging Cell, 2021 - Wiley Online Library
Heart failure (HF) with preserved ejection fraction (HFpEF) is currently the predominant form
of HF with a dramatic increase in risk with age. Low‐grade inflammation, as occurs with …

The aging heart

V Obas, RS Vasan - Clinical Science, 2018 - portlandpress.com
As the elderly segment of the world population increases, it is critical to understand the
changes in cardiac structure and function during the normal aging process. In this review …