Defining physiological normoxia for improved translation of cell physiology to animal models and humans

TP Keeley, GE Mann - Physiological reviews, 2019 - journals.physiology.org
The extensive oxygen gradient between the air we breathe (Po2~ 21 kPa) and its ultimate
distribution within mitochondria (as low as~ 0.5–1 kPa) is testament to the efforts expended …

19F Magnetic Resonance Imaging (MRI): From Design of Materials to Clinical Applications

I Tirotta, V Dichiarante, C Pigliacelli, G Cavallo… - Chemical …, 2015 - ACS Publications
To enable early monitoring of various diseases, to develop noninvasive diagnostic tools,
and to implement targeted therapies are some of the major challenges in current medicine …

Fluorine (19F) MRS and MRI in biomedicine

J Ruiz‐Cabello, BP Barnett, PA Bottomley… - NMR in …, 2011 - Wiley Online Library
Shortly after the introduction of 1H MRI, fluorinated molecules were tested as MR‐detectable
tracers or contrast agents. Many fluorinated compounds, which are nontoxic and chemically …

Advanced functional materials based on polyhedral oligomeric silsesquioxane (POSS)

K Tanaka, Y Chujo - Journal of Materials Chemistry, 2012 - pubs.rsc.org
Polysilsesquioxanes are regarded as organic–inorganic hybrid materials at a molecular
level. We can readily tune the properties of the materials for realizing the desired ones by …

The fluorous effect in biomolecular applications

M Cametti, B Crousse, P Metrangolo, R Milani… - Chemical Society …, 2012 - pubs.rsc.org
From being a niche area only a few decades ago, fluorous chemistry has gained momentum
and is, nowadays, a fervent area of research. It has brought forth, in fact, numerous …

[图书][B] Nucleic acids in chemistry and biology

GM Blackburn - 2006 - books.google.com
The structure, function and reactions of nucleic acids are central to molecular biology and
are crucial for the understanding of complex biological processes involved. Revised and …

Ultrasound-mediated tumor imaging and nanotherapy using drug loaded, block copolymer stabilized perfluorocarbon nanoemulsions

N Rapoport, KH Nam, R Gupta, Z Gao, P Mohan… - Journal of Controlled …, 2011 - Elsevier
Perfluorocarbon nanoemulsions can deliver lipophilic therapeutic agents to solid tumors and
simultaneously provide for monitoring nanocarrier biodistribution via ultrasonography and/or …

19F NMR: a valuable tool for studying biological events

H Chen, S Viel, F Ziarelli, L Peng - Chemical Society Reviews, 2013 - pubs.rsc.org
With the spectacular advancement of NMR techniques and the flourishing of fluorine
chemistry allowing the synthesis of various fluorinated molecules, 19F NMR represents a …

[HTML][HTML] Fluorinated carbohydrates as chemical probes for molecular recognition studies. Current status and perspectives

B Linclau, A Ardá, NC Reichardt, M Sollogoub… - Chemical Society …, 2020 - pubs.rsc.org
This review provides an extensive summary of the effects of carbohydrate fluorination with
regard to changes in physical, chemical and biological properties with respect to regular …

Chemical exchange saturation transfer imaging and spectroscopy

J Zhou, PCM van Zijl - Progress in Nuclear Magnetic Resonance …, 2006 - Elsevier
The study of chemical exchange processes is one of the oldest and still most vigorously
investigated topics in NMR spectroscopy. The effects of chemical exchange on the NMR …