Technological development is in constant progress in the oncological field. The search for
new concepts and strategies for improving cancer diagnosis, treatment and outcomes …

Type 2 diabetes mellitus (T2DM) is a heterogeneous condition that is related to both
defective insulin secretion and peripheral insulin resistance. Beta cells are the major organ …

Although doxorubicin (DOX) is an effective anti-cancer drug with cytotoxicity in a variety of
different tumors, its effectiveness in treating glioblastoma multiforme (GBM) is constrained by …

The bacterial infection that involves antimicrobial resistance is a rising global threat to public
health. Chlorine-based water disinfection processes can inactivate antibiotic resistant …

Faithful genome integrity maintenance plays an essential role in cell survival. Here, we
identify the RNA demethylase ALKBH5 as a key regulator that protects cells from DNA …

A series of multichromophoric ruthenium (II) complexes with the formulation [Ru (tpy-
BODIPY)(tpy-R)] Cl2 (1–4), having a heteroleptic Ru (II)-bis-tpy (tpy= 4′-phenyl-2, 2′: 6 …

Polymerization reactions conducted inside cells must be compatible with the complex
intracellular environment, which contains numerous molecules and functional groups that …

Nanomedicines have been demonstrated as promising strategies for cancer therapy due to
the advantages in pharmacokinetics and drug targeting delivery to tumor tissues. However …

Numerous chemical probes have been used to measure or image oxidative, nitrosative and
related stress induced by free radicals in biology and biochemistry. In many instances, the …

Anacardium occidentale (AO) contains a number of polyphenolic secondary metabolites
with antioxidant activity. The objectives of this study were aimed at investigating the roles of …