Indications and strategy for active surveillance of adult low-risk papillary thyroid microcarcinoma: consensus statements from the Japan Association of Endocrine …

I Sugitani, Y Ito, D Takeuchi, H Nakayama, C Masaki… - Thyroid, 2021 - liebertpub.com
Background: The question of how to manage patients with low-risk papillary thyroid
microcarcinoma (PTMC; T1aN0M0) has recently become an important clinical issue. Two …

Papillary thyroid cancer prognosis: An evolving field

S Ulisse, E Baldini, A Lauro, D Pironi, D Tripodi, E Lori… - Cancers, 2021 - mdpi.com
Simple Summary Over the last couple of decades, the prognostic stratification systems of
differentiated thyroid cancer (DTC) patients have been revised several times in an attempt to …

Papillary thyroid microcarcinoma: time to shift from surgery to active surveillance?

S Leboulleux, RM Tuttle, F Pacini… - The lancet Diabetes & …, 2016 - thelancet.com
The incidence of differentiated thyroid cancer is increasing greatly in high-income countries.
Roughly 50% of this increase is attributable to the identification of intrathyroidal papillary …

Thyroid cancer: risk-stratified management and individualized therapy

F Raue, K Frank-Raue - Clinical Cancer Research, 2016 - AACR
Thyroid cancer is the most common endocrine malignancy. Differentiated thyroid cancer
(DTC) with the two subtypes, papillary thyroid cancer (PTC) and follicular thyroid cancer …

TERT Promoter Mutations in Papillary Thyroid Microcarcinomas

D de Biase, G Gandolfi, M Ragazzi, M Eszlinger… - Thyroid, 2015 - liebertpub.com
Background: Small papillary thyroid carcinomas have contributed to the worldwide
increased incidence of differentiated thyroid cancer observed over the past decades …

BRAF V600E Mutation-Assisted Risk Stratification of Solitary Intrathyroidal Papillary Thyroid Cancer for Precision Treatment

Y Huang, S Qu, G Zhu, F Wang, R Liu… - JNCI: Journal of the …, 2018 - academic.oup.com
Background Precise risk stratification-based treatment of solitary intrathyroidal papillary
thyroid cancer (SI-PTC) that is larger than 1.0 cm and 4.0 cm or less is undefined. Methods A …

Molecular markers involved in tumorigenesis of thyroid carcinoma: focus on aggressive histotypes

GC Penna, F Vaisman, M Vaisman… - … and genome research, 2017 - karger.com
Thyroid cancer derived from follicular cells (TCDFC) comprises well-differentiated (papillary
and follicular) carcinoma, poorly differentiated carcinoma, and anaplastic carcinoma …

Genetic-guided risk assessment and management of thyroid cancer

M Xing - Endocrinology and Metabolism Clinics, 2019 - endo.theclinics.com
Thyroid cancer is a common endocrine malignancy, which histologically includes follicular
epithelial cell–derived thyroid cancer and parafollicular C-cell–derived medullary thyroid …

Obesity Is Associated with BRAFV600E-Mutated Thyroid Cancer

ST Rahman, N Pandeya, RE Neale, DSA McLeod… - Thyroid, 2020 - liebertpub.com
Background: Thyroid cancer incidence has increased in many parts of the world since the
1980s, as has the prevalence of obesity. Evidence suggests that people with greater body …

Clinical use of molecular data in thyroid nodules and cancer

AS Alzahrani - The Journal of Clinical Endocrinology & …, 2023 - academic.oup.com
Over the past 3 decades, advances in the molecular genetics of thyroid cancer (TC) have
been translated into diagnostic tests, prognostic markers, and therapeutic agents. The main …