PURPOSE Squamous cell carcinoma of the anus (SCCA) incidence and mortality rates are
rising in the United States. Understanding state-level incidence and mortality patterns and …

Oncological outcomes are improving in gastrointestinal cancer with advancements in
systemic therapies, and there is notable potential in combining immunotherapy and …

Anal squamous cell carcinoma (ASCC) is a rare gastrointestinal malignancy associated with
high-risk human papillomavirus (HPV) and is currently one of the fastest-growing causes of …

Background The modified docetaxel, cisplatin, and fluorouracil (mDCF) regimen has shown
efficacy and safety as first-line treatment for advanced squamous cell carcinoma of the anus …

Background: The main objectives were to describe the prevalence of HPV, its genotypes
and HPV-associated dysplastic lesions in the oropharyngeal mucosa of PLHIV and related …

Original research: Biomarkers of pembrolizumab efficacy in advanced anal squamous cell
carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders - PMC Back …

Squamous cell carcinoma of the anal canal (SCCA) is a rare neoplasm, but with rising
incidence rates in the past few decades; it is etiologically linked with the human …

As more genetic information becomes available, such as DNA methylation levels, it
becomes increasingly important to have techniques to analyze such data in the context of …

Background and aims Perianal fistulizing Crohn's disease (PFCD)-associated anorectal and
fistula cancers are rare but often devastating diagnoses. However, given the low incidence …

Colorectal (CRC) and anal (AC) cancer, both lower gastrointestinal (GI) cancers vary in their
presentation and treatment. Overall, the incidence of CRC has decreased. However, the …