Microscopic evaluation of the types of cells present in vaginal smears has long been used to
document the stages of the estrous cycle in laboratory rats and mice and as an index of the …

The Norway rat has important impacts on our life. They are amongst the most used research
subjects, resulting in ground-breaking advances. At the same time, wild rats live in close …

Mice are increasingly being used in behavioral neuroscience, largely replacing rats as the
behaviorist's animal of choice. Before aspects of behavior such as emotionality or cognition …

Simple Summary This article reviews the use of non-human animals in biomedical research
from a historical viewpoint, providing an insight into the most relevant social and moral …

This chapter discusses the modulatory influences regulating the timing of puberty in rats.
The developmental process that leads to puberty in the female rat is based on an …

This is an innovative and engaging companion to the language of memory research. It
consists of over 130 entries, bound within a coherent conceptual framework. Each entry …

Reflecting more than a decade's worth of changes, Animal Models in Toxicology, Second
Edition is a practical guide to the common statistical problems encountered in toxicology and …

The laboratory rat was the first mammal domesticated for research purposes. It is descended
from wild Norway rats, Rattus norvegicus, which despite their name likely originated in Asia …

Blood pressure is a quantitative trait that has a strong genetic component in humans and
rats. Several selectively bred strains of rats with divergent blood pressures serve as an …

The rat is an important system for modeling human disease. Four years ago, the rich 150-
year history of rat research was transformed by the sequencing of the rat genome, ushering …