This study aimed to investigate the anti-neuropathic pain activity and its underlying
molecular mechanism of Ajugarin-I (Aju-I) in a rat model of diabetic neuropathic pain. The …

Honokiol is a phytochemical component with a variety of pharmacological properties.
However, the major limitation of Honokiol is its poor solubility and low oral bioavailability. In …

Metabolic disorders, encompassing diabetes mellitus, cardiovascular diseases,
gastrointestinal disorders, etc., pose a substantial global health threat, with rising morbidity …

Background A decrease in nitric oxide (NO) bioavailability has been shown to cause
hyperglycemia, type II diabetes mellitus (DM), and chronic cardio-metabolic complications …

The immune system is one of the essential defense mechanisms. Immune system
inadequacy increases the risk of infections and cancer diseases, whereas over‐activation of …

Introduction: Cardiac fibrosis is strongly induced by diabetic conditions. Both chrysin (CHR)
and calixarene OTX008, a specific inhibitor of galectin 1 (Gal-1), seem able to reduce …

Diabetic peripheral neuropathy (DPN) is a common diabetic complication. Chrysin (CHY)
has many biological properties but poor oral bioavailability. This study investigates the effect …

Purpose The present study was designed to determine the effect of levofloxacin (LVX)
treatment on the blood glucose level, insulin sensitivity, anxiety level, nitrite and MDA level …

Cadmium (Cd) is a serious environmental pollutant affecting various tissues/organs in
broilers and compromising their immunological function and productivity. Therefore, the …

Abstract Background The Ancient system of medicine showed the limelight on the use of
herbal remedies and was found to possess minimal side effects and acceptable therapeutic …