Approximately 5% of the world-wide population is affected by autoimmune diseases.
Overall, autoimmune diseases are still difficult to treat, impose a high burden on patients …

Pulmonary arterial hypertension (PAH) is a devastating disease that involves pulmonary
vasoconstriction, small vessel obliteration, large vessel thickening and obstruction, and …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common life-
threatening lung diseases associated with acute and severe inflammation. Both have high …

Exosomes are small vesicles (30–150 nm in diameter) enclosed by a lipid membrane
bilayer, secreted by most cells in the body. They carry various molecules, including proteins …

Inflammation plays an important role in cardiac injuries. Here, we examined the role of
miRNA in regulating inflammation and cardiac injury during myocardial infarction. We …

Exosomes are small extracellular vesicles that are secreted by almost all types of cells and
exist in almost all extracellular spaces. As an important mediator of intercellular …

The vascular response to pro-atherosclerotic factors is a multifactorial process involving
endothelial cells (ECs), macrophages (MACs), and smooth muscle cells (SMCs), although …

The lung is the organ with the highest vascular density in the human body. It is therefore
perceivable that the endothelium of the lung contributes significantly to the circulation of …

Rationale: Currently, there are no blood-based biomarkers with clinical utility for acute
ischemic stroke (IS). MicroRNAs show promise as disease markers because of their cell type …

Mesenchymal stem cells (MSCs) exert therapeutic effect on treating acute myocardial
infarction. Recent evidence showed that paracrine function rather than direct differentiation …