The accumulation of amyloid fibrils is characteristic of neurodegenerative diseases such as
Alzheimer's disease (AD) and Parkinson's disease. Detecting these fibrils with fluorescent or …

The identification and detection of disease-related biomarkers is essential for early clinical
diagnosis, evaluating disease progression, and for the development of therapeutics …

A series of novel styryl dye derivatives incorporating indolium and quinolinium core
structures were successfully synthesized to explore their interacting and binding capabilities …

Fluorescent probes are a powerful tool for imaging amyloid β (Aβ) plaques, the hallmark of
Alzheimer's disease (AD). Herein, we report the synthesis and comprehensive …

Viscosity, an essential parameter of the cellular microenvironment, has the ability to indicate
the condition of living cells. It is closely linked to numerous diseases like Alzheimer's …

The typical neurodegenerative Alzheimer's disease (AD) poses an increasing threat to
human health as the population ages. Though increasing attention has been drawn for the …

Recently, some near-infrared fluorescent (NIRF) probes targeting a toxic form of Aβ
aggregate,“Aβ oligomer”, have been developed as useful imaging tools in various situations …

Macrocyclic polyamines constitute a significant class of macrocyclic compounds that play a
pivotal role in the realm of supramolecular chemistry. They find extensive applications …

Cyclometallated Pt (II) complexes possessing hydrophobic 2-phenylpyridine (ppy) ligands
and hydrophilic acetonylacetone (acac) ligands have been investigated for their ability to …

Alzheimer's disease (AD) is the most common form of neurodegenerative dementia that is
rapidly becoming a major health problem, especially in developed countries because of …