Abstract The glycoprotein alpha-1-antichymotrypsin (AACT), a serine protease inhibitor, is
mainly synthesized in the liver and then secreted into the blood and is involved in the acute …

The field of proteomics is undergoing rapid development in a number of different areas
including improvements in mass spectrometric platforms, peptide identification algorithms …

In this study, the human cerebrospinal fluid (CSF) proteome was mapped using three
different strategies prior to Orbitrap LC-MS/MS analysis: SDS-PAGE and mixed mode …

Purpose Multiple sclerosis is the first cause of progressive neurological disability among
young adults living in W estern countries. Its diagnosis is mostly based on clinical …

A low dose of 1 μg rhBMP-2 was immobilised by four different functionalising techniques on
recently developed poly (l-lactide)-co-(ε-caprolactone)[(poly (LLA-co-CL)] scaffolds. It was …

Apolipoprotein D is a chordate gene early originated in the Lipocalin protein family. Among
other features, regulation of its expression in a wide variety of disease conditions in humans …

Contactins are a group of cell adhesion molecules that are mainly expressed in the brain
and play pivotal roles in the organization of axonal domains, axonal guidance …

Multiple Sclerosis (MS) is a demyelinating disease of the human central nervous system
having an unconfirmed pathoetiology. Although animal models are used to mimic the …

Many disease processes in the brain are reflected in the protein composition of the
cerebrospinal fluid (CSF). In addition to proteins, CSF also contains a large number of …

Cerebrospinal fluid is investigated in biomarker studies for various neurological disorders of
the central nervous system due to its proximity to the brain. Currently, only a limited number …