Intrinsic, widefield optical imaging of hemodynamics in rodent models of Alzheimer's disease and neurological injury
The complex cerebrovascular network is critical to controlling local cerebral blood flow
(CBF) and maintaining brain homeostasis. Alzheimer's disease (AD) and neurological injury …
(CBF) and maintaining brain homeostasis. Alzheimer's disease (AD) and neurological injury …
From 1901 to 2022, how far are we from truly understanding the pathogenesis of age-related dementia?
From the first described AD case in 1901 to the current year 2022, understanding the
pathogenesis of Alzheimer's disease (AD) and dementia has undergone a long and tortuous …
pathogenesis of Alzheimer's disease (AD) and dementia has undergone a long and tortuous …
Preserved blood-brain barrier and neurovascular coupling in female 5xFAD model of Alzheimer's disease
O Zhukov, C He, R Soylu-Kucharz, C Cai… - Frontiers in Aging …, 2023 - frontiersin.org
Dysfunction of the cerebral vasculature is considered one of the key components of
Alzheimer's disease (AD), but the mechanisms affecting individual brain vessels are poorly …
Alzheimer's disease (AD), but the mechanisms affecting individual brain vessels are poorly …
Optical Devices for the Diagnosis and Management of Spinal Cord Injuries: A Review
Throughout the central nervous system, the spinal cord plays a very important role, namely,
transmitting sensory and motor information inwardly so that it can be processed by the brain …
transmitting sensory and motor information inwardly so that it can be processed by the brain …
Cortical microvascular blood flow velocity mapping by combining dynamic light scattering optical coherence tomography and two-photon microscopy
Significance The accurate large-scale mapping of cerebral microvascular blood flow velocity
is crucial for a better understanding of cerebral blood flow (CBF) regulation. Although optical …
is crucial for a better understanding of cerebral blood flow (CBF) regulation. Although optical …
[PDF][PDF] Revisiting the effects of exercise on cerebral neurovascular functions in rats using multimodal assessment techniques
S Yen, HY Wu, Y Wang, CM Huang, CW Wu, JH Chen… - Iscience, 2023 - cell.com
Physical activity in the form of aerobic exercise has many beneficial effects on brain function.
Here, we aim to revisit the effects of exercise on brain morphology and neurovascular …
Here, we aim to revisit the effects of exercise on brain morphology and neurovascular …
Extracellular Alterations in pH and K+ Modify the Murine Brain Endothelial Cell Total and Phospho-Proteome
JR Wahl, A Vivek, SM Palomino, M Almuslim… - Pharmaceutics, 2022 - mdpi.com
Pathologies of the blood–brain barrier (BBB) have been linked to a multitude of central
nervous system (CNS) disorders whose pathology is poorly understood. Cortical spreading …
nervous system (CNS) disorders whose pathology is poorly understood. Cortical spreading …
[HTML][HTML] Behavioral and neural activity-dependent recanalization of plugged capillaries in the brain of adult and aged mice
P Reeson, B Schager, M Van Sprengel… - Frontiers in Cellular …, 2022 - frontiersin.org
The capillaries of the brain, owing to their small diameter and low perfusion pressure, are
vulnerable to interruptions in blood flow. These tiny occlusions can have outsized …
vulnerable to interruptions in blood flow. These tiny occlusions can have outsized …
Low-invasive neural recording in mouse models with diabetes via an ultrasmall needle-electrode
R Sanda, K Yamashita, H Sawahata… - Biosensors and …, 2023 - Elsevier
Diabetes is known to cause a variety of complications, having a high correlation with
Alzheimer's disease. Electrophysiological recording using a microscale needle electrode is …
Alzheimer's disease. Electrophysiological recording using a microscale needle electrode is …
Depression of dynamic cerebral autoregulation during neural activation: the role of responders and non-responders
K Ladthavorlaphatt, FBS Surti… - Journal of Cerebral …, 2024 - journals.sagepub.com
Neurovascular coupling (NVC) interaction with dynamic cerebral autoregulation (dCA)
remains unclear. We investigated the effect of task complexity and duration on the …
remains unclear. We investigated the effect of task complexity and duration on the …