[HTML][HTML] Dolutegravir resistance in sub-Saharan Africa: should resource-limited settings be concerned for future treatment?

D Kamori, G Barabona - Frontiers in Virology, 2023 - frontiersin.org
In sub-Saharan Africa (SSA) the burden of non-nucleoside reverse transcriptase inhibitor
(NNRTI) HIV drug resistance (HIVDR) has been high over the years. Therefore, in 2018 the …

[HTML][HTML] HIV-1 diversity and pre-treatment drug resistance in the era of integrase inhibitor among newly diagnosed ART-naïve adult patients in Luanda, Angola

CS Sebastião, AB Abecasis, D Jandondo… - Scientific Reports, 2024 - nature.com
The surveillance of drug resistance in the HIV-1 naïve population remains critical to
optimizing the effectiveness of antiretroviral therapy (ART), mainly in the era of integrase …

[HTML][HTML] Low level of HIV-1C integrase strand transfer inhibitor resistance mutations among recently diagnosed ART-naive Ethiopians

M Kiros, DA Tefera, H Andualem, A Geteneh… - Scientific Reports, 2023 - nature.com
With the widespread use of Integrase strand transfer inhibitors (INSTIs), surveillance of HIV-
1 pretreatment drug resistance is critical in optimizing antiretroviral treatment efficacy …

[HTML][HTML] Comprehensive Analysis of HIV-1 Integrase Resistance-Related Mutations in African Countries

F Branda, M Giovanetti, L Sernicola, S Farcomeni… - Pathogens, 2024 - mdpi.com
The growing emergence of non-nucleoside reverse transcriptase inhibitor (NNRTI) HIV drug
resistance in sub-Saharan Africa (SSA) led to the World Health Organization (WHO) …

[HTML][HTML] Interaction analysis of statistically enriched mutations identified in Cameroon recombinant subtype CRF02_AG that can influence the development of …

SG Mikasi, D Isaacs, R Chitongo, GM Ikomey… - BMC infectious …, 2021 - Springer
Abstract Background The Integrase (IN) strand transfer inhibitor (INSTI), Dolutegravir (DTG),
has been given the green light to form part of first-line combination antiretroviral therapy …

[PDF][PDF] HIV-1 diversity and the implementation of integrase strand-transfer inhibitors as part of combination antiretroviral therapy

SG Mikasi, GM Ikomey, AE Obasa, R Cloete… - 2020 - infospace.mrc.ac.za
To the Editor: The integrase (IN) strand-transfer inhibitor (InSTI) dolutegravir (DTG) is now
recommended by the World Health Organization as part of salvage and/or first-line …