A new role for old friends: effects of helminth infections on vaccine efficacy

F Zhu, W Liu, T Liu, L Shi, W Zheng, F Guan, J Lei - Pathogens, 2022 - mdpi.com
Vaccines are one of the most successful medical inventions to enable the eradication or
control of common and fatal diseases. Environmental exposure of hosts, including helminth …

Influence of schistosomiasis on host vaccine responses

JK Nono, SD Kamdem, F Musaigwa, CA Nnaji… - Trends in …, 2022 - cell.com
Schistosomiasis is a debilitating helminthiasis which commonly establishes as a chronic
infection in people from endemic areas. As a potent modulator of the host immune response …

Schistosoma mansoni infection alters the host pre-vaccination environment resulting in blunted Hepatitis B vaccination immune responses

R Muir, T Metcalf, S Fourati, Y Bartsch… - PLoS neglected …, 2023 - journals.plos.org
Schistosomiasis is a disease caused by parasitic flatworms of the Schistosoma spp., and is
increasingly recognized to alter the immune system, and the potential to respond to …

Intestinal Helminth Infection Impairs Oral and Parenteral Vaccine Efficacy

Y Zhang, LKC Hardy, CM Kapita, JA Hall… - The Journal of …, 2023 - journals.aai.org
The impact of endemic parasitic infection on vaccine efficacy is an important consideration
for vaccine development and deployment. We have examined whether intestinal infection …

The effects of helminth infections on the human gut microbiome: a systematic review and meta-analysis

B Walusimbi, MAE Lawson, J Nassuuna… - Frontiers in …, 2023 - frontiersin.org
The gut microbiome is important in shaping human health. One key factor that has been
proposed to affect the gut microbiome is helminth infection. Unravelling the association …

Intestinal helminth infection impairs oral and parenteral vaccine efficacy

LKC Hardy, CM Kapita, E Campbell, JA Hall… - bioRxiv, 2022 - biorxiv.org
The impact of endemic parasitic infection on vaccine efficacy is an important consideration
for vaccine development and deployment. We have examined whether intestinal infection …

NIHR Global Health Research Group on Vaccines for vulnerable people in Africa (VAnguard): Concept and Launch event report

L Zirimenya, F Zalwango, EA Owino… - NIHR Open …, 2024 - openresearch.nihr.ac.uk
Background Vaccination is an important public health intervention, but not everyone benefits
equally. Biological, social and structural factors render some communities vulnerable and …

As helmintíases, doenças tropicais negligenciadas, podem afetar a eficácia das vacinas? Com ênfase na COVID-19

GAS Roque, PH Gallo-Francisco, M Flóro… - BioEns …, 2023 - econtents.bc.unicamp.br
Helmintíases são doenças negligenciadas, estão entre as parasitoses mais comuns em
países em desenvolvimento, e podem modular negativamente as respostas imunes anti …

Exploiting CD22 on B Cells to Prevent Sensitization and to Induce Lasting Immune Tolerance in Murine Models of Peanut Allergy

LKC Hardy - 2022 - search.proquest.com
Severe peanut allergy is driven by B cell-derived, allergen-specific IgE. Early introduction of
peanut proteins into the diet is the only clinically-validated strategy to protect against peanut …

[PDF][PDF] A New Role for Old Friends: Effects of Helminth Infections on Vaccine Efficacy. Pathogens 2022, 11, 1163

F Zhu, W Liu, T Liu, L Shi, W Zheng, F Guan, J Lei - 2022 - academia.edu
Vaccines are one of the most successful medical inventions to enable the eradication or
control of common and fatal diseases. Environmental exposure of hosts, including helminth …