The yeast cell wall is a highly dynamic structure that is responsible for protecting the cell
from rapid changes in external osmotic potential. The wall is also critical for cell expansion …

Pathogenic fungi are a major causative group for opportunistic infections (OIs). AIDS
patients and other immunocompromised individuals are at risk for OIs, which if not treated …

There are currently few antifungals in use which show efficacy against fungal diseases.
These antifungals mostly target specific components of fungal plasma membrane or its …

Covering: 31st December 2004Natural product and natural product-derived compounds that
are being evaluated in clinical trials or in registration (current 31 December 2004) have …

The RNA-guided DNA editing technology CRISPRs (clustered regularly interspaced short
palindromic repeats)/Cas9 had been used to introduce double-stranded breaks into …

Increase in invasive fungal infections over the past few years especially in
immunocompromised patients prompted the search for new antifungal agents with improved …

The series of quinoline derivatives were prepared. The synthetic approach, analytical, and
spectroscopic data of all synthesized compounds are presented. All the prepared derivatives …

In the present study, we have synthesized 2-(substituted phenyl)-1H-imidazole (1–12) and
(substituted phenyl)-[2-(substituted phenyl)-imidazol-1-yl]-methanone (13–26) analogues …

Although the assortment of antifungal drugs is broad, the most commonly used agents have
major drawbacks. Toxicity, serious side effects or the emergence of drug resistance are …

Although of less importance than their R-analogues, β-amino acids are also present in
peptides and different heterocycles, and their free forms and derivatives exhibit interesting …