Arrhythmia-induced cardiomyopathy (AIC) is a potentially reversible condition in which left
ventricular dysfunction is induced or mediated by atrial or ventricular arrhythmias. Cellular …

Arrhythmia means the heart is beating too fast, too slow, or with an irregular pattern. Due to
the side effects and low bioavailability of many antiarrhythmic drugs, nano-encapsulation …

The electrocardiogram, also known as an electrocardiogram (ECG), is considered to be one
of the most significant sources of data regarding the structure and function of the heart. In …

Electrophysiological and structural disruptions in cardiac arrhythmias are closely related to
mitochondrial dysfunction. Mitochondria are an organelle generating ATP, thereby satisfying …

CD38 enzymatic activity regulates NAD+ and cADPR levels in mammalian tissues, and
therefore has a prominent role in cellular metabolism and calcium homeostasis …

Background Permanent junctional reciprocating tachycardia (PJRT) is an uncommon form of
supraventricular tachycardia in children. Treatment of this arrhythmia has been considered …

Cardiac muscle contraction is a strictly regulated process which conjugates a series of
electrophysiological, biochemical and mechanic events, resulting in the pumping of blood to …

Background Mutations in the PRKAG2 gene encoding the γ-subunit of adenosine
monophosphate kinase (AMPK) cause hypertrophic cardiomyopathy (HCM) and familial …

Arrhythmias arise from breakdown of orderly action potential (AP) activation, propagation
and recovery driven by interactive opening and closing of successive voltage-gated ion …

Previous studies have linked dysfunctional I to arising from mutations to KCND3-encoded
Kv4. 3 and KCND2-encoded Kv4. 2 to atrial fibrillation. Using computational models, this …